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急性和慢性肺栓塞的外科治疗。

Surgical Management of Acute and Chronic Pulmonary Embolism.

机构信息

Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina, 130 Mason Farm Road CB 7020, Chapel Hill, NC 27599, USA.

Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

出版信息

Clin Chest Med. 2018 Sep;39(3):659-667. doi: 10.1016/j.ccm.2018.04.017.

Abstract

Surgical pulmonary embolectomy and pulmonary thromboendarterectomy are well-established treatment strategies for patients with acute and chronic pulmonary embolism, respectively. For both procedures, techniques and outcomes have evolved considerably over the past decades. Patients with massive and submassive acute pulmonary embolism are at risk for rapid decline owing to right ventricular failure and shock. When thrombus is proximal, embolectomy can rapidly restore cardiac function. Chronic thromboembolic pulmonary hypertension is a more complex disease that requires skilled, careful dissection of the arterial wall, including vascular intima. When successful, surgery leads to clinical cure of the associated pulmonary hypertension, with excellent long-term outcomes.

摘要

外科肺动脉血栓切除术和肺动脉血栓内膜切除术分别是急性和慢性肺栓塞患者的成熟治疗策略。这两种手术的技术和结果在过去几十年中都有了很大的发展。患有大量和次大量急性肺栓塞的患者由于右心衰竭和休克而有迅速恶化的风险。当血栓位于近端时,血栓切除术可以迅速恢复心脏功能。慢性血栓栓塞性肺动脉高压是一种更为复杂的疾病,需要熟练、仔细地分离动脉壁,包括血管内膜。如果手术成功,可治愈相关肺动脉高压,长期预后极佳。

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