Burt R W, Samowitz W S
Department of Internal Medicine, University of Utah, Salt Lake City.
Gastroenterol Clin North Am. 1988 Dec;17(4):657-78.
Adenomatous polyps are the benign precursors of colorectal adenocarcinoma. Colonic adenomas occur commonly in adults in Western countries. There is recent evidence that inheritance may play an important role in the etiology of these adenomatous polyps. Colonic adenomatous polyposis (numerous colonic adenomas) is the central feature of several rare inherited syndromes that give rise to colorectal cancer. There also appears to be a risk of gastrointestinal and other malignancies in the rare inherited syndromes of hamartomatous polyposis.
腺瘤性息肉是结直肠癌的良性前驱病变。结肠腺瘤在西方国家成年人中常见。最近有证据表明，遗传因素可能在这些腺瘤性息肉的病因中起重要作用。结肠腺瘤性息肉病（大量结肠腺瘤）是几种罕见的遗传性综合征的核心特征，这些综合征会引发结直肠癌。在错构瘤性息肉病的罕见遗传性综合征中，似乎也存在胃肠道及其他恶性肿瘤的风险。
