Horváth K K, Ormos J, Ribári O
Ultrastruct Pathol. 1986;10(3):257-64. doi: 10.3109/01913128609032225.
The morphologic features of a jugulotympanic paraganglioma are reported. The tumor showed the usual histology of paragangliomas. No sustentacular cells were identified. In the tumorous chief cells there were typical neurosecretory dense-core granules 60-180 nm in diameter. Granules averaging 400 nm in diameter were also observed, sometimes with a regular rhomboid core or crystallized content. Rhomboid crystals were seen in the cytoplasm in membrane-bound spaces and in telolysosomes. The crystals had a substructure consisting of alternating light and dark lines with a periodocity of 5-10 nm. Such crystals had not been reported previously in paragangliomas. The possible origin of the crystals is discussed.
本文报告了颈静脉鼓室副神经节瘤的形态学特征。该肿瘤具有副神经节瘤常见的组织学表现。未发现支持细胞。在肿瘤主细胞中可见直径60 - 180 nm的典型神经分泌致密核心颗粒。还观察到平均直径为400 nm的颗粒，有时具有规则的菱形核心或结晶内容物。在膜结合空间的细胞质和终末溶酶体中可见菱形晶体。这些晶体具有由明暗相间的线条交替组成的亚结构，周期为5 - 10 nm。此前在副神经节瘤中尚未有此类晶体的报道。文中讨论了这些晶体的可能来源。
