Chaudhry A P, Haar J G, Koul A, Nickerson P A
Cancer. 1979 May;43(5):1689-701. doi: 10.1002/1097-0142(197905)43:5<1689::aid-cncr2820430520>3.0.co;2-5.
The clinical, histological, and ultrastructural aspects of a cervical paraganglioma of the vagus nerve, in a 66-year-old white man, have been discussed in detail. Ultrastructurally, the tumor chief cells contained characteristic membrane-bound and dense-cored neurosecretory granules which ranged in size from 85 millimicron to 190 millimicron. Unlike earlier ultrastructural reports, the present study showed the presence of sustentacular or supporting cells. These cells were smaller, darker, polymorphic, and were commonly located at the periphery of a single or group of chief cells. Furthermore, unlike earlier reports on vagal paragangliomas, nonmyelinated nerve fibers and an occasional axon were identified in the present fine structure study.
详细讨论了一名66岁白人男性迷走神经颈副神经节瘤的临床、组织学和超微结构特征。在超微结构上，肿瘤主细胞含有特征性的膜结合致密核心神经分泌颗粒，大小从85毫微米到190毫微米不等。与早期的超微结构报告不同，本研究显示存在支持细胞。这些细胞较小、颜色较深、形态多样，通常位于单个或一组主细胞的周边。此外，与早期关于迷走神经副神经节瘤的报告不同，在本精细结构研究中发现了无髓神经纤维和偶尔的轴突。
