Smith J R, Johnson R H
Vet Rec. 1986 Apr 5;118(14):385-7. doi: 10.1136/vr.118.14.385.
Data are presented on studies of field and experimental use of a formalin-inactivated canine parvovirus vaccine. There was an absolute correlation between a single successful vaccination and subsequent protection against clinical disease. Unsuccessful vaccinations were consistently associated with the presence of maternal antibody at the time of vaccination. The vaccine induced an antibody response within two days and anamnestic responses within 24 hours. It is suggested that a single successful vaccination probably protects against clinical parvovirus disease for life.
本文展示了关于福尔马林灭活犬细小病毒疫苗的田间和实验使用研究的数据。单次成功接种疫苗与随后预防临床疾病之间存在绝对相关性。接种失败始终与接种时母源抗体的存在有关。该疫苗在两天内诱导抗体反应，在24小时内诱导回忆反应。有人认为，单次成功接种疫苗可能终生预防临床细小病毒病。
