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淋巴结移植治疗淋巴水肿。

Lymph node transplantation for the treatment of lymphedema.

作者信息

Gould Daniel J, Mehrara Babak J, Neligan Peter, Cheng Ming-Huei, Patel Ketan M

机构信息

Division of Plastic and Reconstructive Surgery, University of Southern California, California.

Department of Surgery, Plastic and Reconstructive Surgery, Service, Memorial Sloan-Kettering Cancer Center, New York.

出版信息

J Surg Oncol. 2018 Oct;118(5):736-742. doi: 10.1002/jso.25180. Epub 2018 Aug 21.

Abstract

Lymphedema is a complex disease process with deranged lymphatic transport, fluid accumulation and secondary lipedema and fibrosis. This is a challenging disease to treat with a surgical focus on debulking and physiologic strategies. One strategy is the use of vascularized lymph node transplant (VLNT) to improve physiologic lymph clearance. In this article, VLNT is discussed in detail, including mechanisms, combined strategies, and outcomes.

摘要

淋巴水肿是一种复杂的疾病过程,伴有淋巴转运紊乱、液体蓄积以及继发性脂肪水肿和纤维化。这是一种具有挑战性的疾病,治疗重点在于手术减容和生理策略。一种策略是使用带血管蒂淋巴结移植(VLNT)来改善生理性淋巴清除。在本文中,将详细讨论带血管蒂淋巴结移植,包括其机制、联合策略和结果。

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