IEEE Trans Biomed Eng. 2019 Apr;66(4):967-976. doi: 10.1109/TBME.2018.2865751. Epub 2018 Aug 17.
To demonstrate the feasibility of everaging impedance plethysmography (IPG) for detection of pulse transit time (PTT) and estimation of blood pressure (BP).
We first established the relationship between BP, PTT, and arterial impedance (i.e., the IPG observations). The IPG sensor was placed on the wrist while the photoplethysmography sensor was attached to the index finger to measure the PTT. With a cuff-based BP monitoring system placed on the upper arm as a reference, our proposed methodology was evaluated on 15 young, healthy human subjects leveraging handgrip exercises to manipulate BP/PTT and compared to several conventional PTT models to assess the efficacy of PTT/BP detections.
The proposed model correlated with BP fairly well with group average correlation coefficients of [Formula: see text] for systolic BP (SBP) and [Formula: see text] for diastolic BP (DBP). In comparison with the other PTT methods, PTT-IPG-based BP estimation provided a lower root-mean-squared-error of [Formula: see text] and [Formula: see text] for SBP and DBP, respectively.
We conclude that the measurement of arterial impedance via IPG methods is an adequate indicator to estimate BP. The proposed method appears to offer superiority compared to the conventional PTT estimation approaches.
Using impedance magnitude to estimate PTT offers promise to realize wearable and cuffless BP devices.
展示平均阻抗体积描记法（IPG）检测脉搏传导时间（PTT）和估计血压（BP）的可行性。
我们首先建立了 BP、PTT 和动脉阻抗之间的关系（即 IPG 观测值）。将 IPG 传感器放置在手腕上，同时将光体积描记传感器附在食指上以测量 PTT。利用置于上臂的基于袖带的 BP 监测系统作为参考，我们的方法在 15 名年轻健康的人体受试者中进行了评估，利用手握运动来操纵 BP/PTT，并与几种传统的 PTT 模型进行比较，以评估 PTT/BP 检测的效果。
所提出的模型与 BP 相关性较好，收缩压（SBP）的组平均相关系数为[Formula: see text]，舒张压（DBP）的组平均相关系数为[Formula: see text]。与其他 PTT 方法相比，基于 PTT-IPG 的 BP 估计提供了较低的均方根误差，分别为[Formula: see text]和[Formula: see text]用于 SBP 和 DBP。
我们得出结论，通过 IPG 方法测量动脉阻抗是估计 BP 的有效指标。与传统的 PTT 估计方法相比，所提出的方法似乎具有优越性。
使用阻抗幅度来估计 PTT 有望实现可穿戴和无袖带的 BP 设备。
