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炎症性肠病内镜指数的编年回顾

Chronological Review of Endoscopic Indices in Inflammatory Bowel Disease.

作者信息

Lee Joon Seop, Kim Eun Soo, Moon Won

机构信息

Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.

出版信息

Clin Endosc. 2019 Mar;52(2):129-136. doi: 10.5946/ce.2018.042. Epub 2018 Aug 21.

Abstract

Inflammatory bowel disease (IBD) is considered a chronic condition characterized by mucosal or transmural inflammation in the gastrointestinal tract. Endoscopic diagnosis and surveillance in patients with IBD have become crucial. In addition, endoscopy is a useful modality in estimation and evaluation of the disease, treatment results, and efficacy of treatment delivery and surveillance. In relation to these aspects, endoscopic disease activity has been commonly estimated in clinical practices and trials.
At present, many endoscopic indices of ulcerative colitis have been introduced, including the Truelove and Witts Endoscopy Index, Baron Index, Powell-Tuck Index, Sutherland Index, Mayo Clinic Endoscopic Sub-Score, Rachmilewitz Index, Modified Baron Index, Endoscopic Activity Index, Ulcerative Colitis Endoscopic Index of Severity, Ulcerative Colitis Colonoscopic Index of Severity, and Modified Mayo Endoscopic Score. Endoscopic indices have been also suggested for Crohn's disease, such as the Crohn's Disease Endoscopic Index of Severity, Simple Endoscopic Score for Crohn's Disease, and Rutgeerts Postoperative Endoscopic Index. However, most endoscopic indices have not been validated owing to the complexity of their parameters and inter-observer variations. Therefore, a chronological approach for understanding the various endoscopic indices relating to IBD is needed to improve the management.

摘要

炎症性肠病(IBD)被认为是一种以胃肠道黏膜或透壁性炎症为特征的慢性疾病。IBD患者的内镜诊断和监测已变得至关重要。此外,内镜检查是评估疾病、治疗结果以及治疗实施和监测效果的一种有用方式。关于这些方面,内镜下疾病活动度在临床实践和试验中已得到普遍评估。

目前,已引入了许多溃疡性结肠炎的内镜指数,包括特鲁洛夫和维茨内镜指数、巴伦指数、鲍威尔 - 塔克指数、萨瑟兰指数、梅奥诊所内镜子评分、拉赫米列维茨指数、改良巴伦指数、内镜活动指数、溃疡性结肠炎内镜严重程度指数、溃疡性结肠炎结肠镜严重程度指数以及改良梅奥内镜评分。也有人提出了克罗恩病的内镜指数,如克罗恩病内镜严重程度指数、克罗恩病简易内镜评分以及鲁杰尔斯术后内镜指数。然而,由于其参数的复杂性和观察者间差异,大多数内镜指数尚未得到验证。因此,需要一种按时间顺序的方法来理解与IBD相关的各种内镜指数,以改善管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4468/6453843/0e6b019db611/ce-2018-042f1.jpg

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