Cookson W O, De Klerk N H, Musk A W, Armstrong B K, Glancy J J, Hobbs M S
Br J Ind Med. 1986 Jul;43(7):450-7. doi: 10.1136/oem.43.7.450.
An estimate has been made of the prevalence of unrecognised pneumoconiosis in former crocidolite workers from Wittenoom, Western Australia. All plain chest radiographs relating to a one in six random sample (1025 men) of all former Wittenoom workers who had never entered a compensation claim to the Pneumoconiosis Medical Board of Western Australia were sought from Perth teaching hospitals and from the Perth Chest Clinic where compulsory examination of all workers in the mining industry takes place. Radiographs were recovered for 83% of the men and read independently by two observers. By means of logistic regression analysis a current prevalence of parenchymal abnormality (defined as a radiographic profusion of small opacities of category 1/0 or greater on the ILO classification) of nearly 20% was calculated after adjustment for age, time since first exposure, and cumulative exposure level. One hundred men randomly selected from those known to be alive in the sample were invited to attend for a new radiographic examination. Seventy four men attended and the predicted prevalence was confirmed. It is estimated from these data that there were between 450 and 900 former Wittenoom workers in Australia at the end of 1980 who had radiographic abnormality consistent with pneumoconiosis but had not claimed compensation or had asbestosis diagnosed. The data are consistent with there being no threshold dose of crocidolite exposure for the development of radiographic abnormality in this group.
对西澳大利亚州维特努姆地区前青石棉工人中未被识别的尘肺病患病率进行了估计。从珀斯的教学医院以及珀斯胸部诊所(这里会对采矿业所有工人进行强制检查)获取与西澳大利亚州尘肺病医疗委员会所有从未提出过赔偿申请的前维特努姆工人六分之一随机样本(1025名男性)相关的所有胸部X光平片。83%的男性的X光片被找回,并由两名观察者独立阅片。通过逻辑回归分析,在对年龄、首次接触后的时间以及累积接触水平进行调整后,计算出实质性异常(根据国际劳工组织分类,定义为小阴影密集度为1/0级或更高的X光片表现)的当前患病率接近20%。从已知在世的样本中随机挑选100名男性邀请他们参加新的X光检查。74名男性参加了检查,预测的患病率得到了证实。根据这些数据估计,在1980年末,澳大利亚有450至900名前维特努姆工人,他们的X光片异常与尘肺病相符,但未提出赔偿申请或被诊断为石棉沉着病。这些数据表明,在该群体中,青石棉接触剂量不存在导致X光片异常的阈值。