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Development of an immunofluorescence test for the serodiagnosis of herpes zoster ophthalmicus.

作者信息

Walpita P, Darougar S, Marsh R J, Cooper M

出版信息

Br J Ophthalmol. 1986 Jun;70(6):431-4. doi: 10.1136/bjo.70.6.431.

DOI:10.1136/bjo.70.6.431
PMID:3013281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1041035/
Abstract

An indirect immunofluorescence test has been developed and evaluated for the serodiagnosis of herpes zoster ophthalmicus (HZO) by the detection of antivaricella zoster virus (VZV) antibody. The results show that, in patients with HZO, anti-VZV IgG antibody titre usually rises rapidly after onset. One hundred and seven of the 134 sera (80%) from patients with a clinical diagnosis of HZO had an anti-VZV IgG titre of greater than or equal to 256, and IgM antibody at a level of 1 in 8 was present in six of them. In comparison only two of the 216 sera (1%) from patients with a clinical diagnosis of ocular infections other than those caused by VZV had such IgG titres. It was concluded that, on the basis of results of a single sample of serum, it is possible to make a provisional diagnosis of HZO with a high degree of confidence.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0229/1041035/ef841e631901/brjopthal00628-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0229/1041035/600b48dc96fb/brjopthal00628-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0229/1041035/ef841e631901/brjopthal00628-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0229/1041035/600b48dc96fb/brjopthal00628-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0229/1041035/ef841e631901/brjopthal00628-0034-a.jpg

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本文引用的文献

1
COMPARATIVE SENSITIVITY OF HUMAN FETAL DIPLOID KIDNEY CELL STRAINS AND MONKEY KIDNEY CELL CULTURES FOR ISOLATION OF CERTAIN HUMAN VIRUSES.人胎儿二倍体肾细胞株与猴肾细胞培养物对某些人病毒分离的比较敏感性
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2
Fading of immunofluorescence during microscopy: a study of the phenomenon and its remedy.显微镜检查过程中免疫荧光的消退：对该现象及其补救方法的研究。
J Immunol Methods. 1982 Dec 17;55(2):231-42. doi: 10.1016/0022-1759(82)90035-7.
3
A comparison of indirect immunofluorescence and radioimmunoassay for detecting antibody to varicella-zoster virus.
间接免疫荧光法与放射免疫分析法检测水痘-带状疱疹病毒抗体的比较
J Virol Methods. 1983 Mar;6(3):135-40. doi: 10.1016/0166-0934(83)90025-3.
4
Detection of antibody to varicella-zoster virus by competitive and IgM-antibody capture immunoassay.采用竞争法和IgM抗体捕获免疫测定法检测水痘-带状疱疹病毒抗体。
J Med Virol. 1981;8(2):89-101. doi: 10.1002/jmv.1890080203.
5
Rapid diagnosis of varicella-zoster virus infections by countercurrent immunoelectrophoresis.通过对流免疫电泳快速诊断水痘-带状疱疹病毒感染。
J Infect Dis. 1981 Feb;143(2):274-80. doi: 10.1093/infdis/143.2.274.
6
Immunoglobulins M and G to varicella-zoster virus measured by solid-phase radioimmunoassay: antibody responses to varicella and herpes zoster infections.通过固相放射免疫测定法检测的针对水痘-带状疱疹病毒的免疫球蛋白M和G：对水痘和带状疱疹感染的抗体反应
J Clin Microbiol. 1980 Sep;12(3):367-74. doi: 10.1128/jcm.12.3.367-374.1980.
7
Indirect micro-immunofluorescence test for detecting type-specific antibodies to herpes simplex virus.用于检测单纯疱疹病毒型特异性抗体的间接微量免疫荧光试验。
J Clin Pathol. 1980 Feb;33(2):171-6. doi: 10.1136/jcp.33.2.171.
8
Herpes zoster keratitis.带状疱疹性角膜炎
Trans Ophthalmol Soc U K (1962). 1973;93(0):181-92.
9
Varicella virus in HeLa cells.水痘病毒在海拉细胞中的情况。
Arch Gesamte Virusforsch. 1965;17(3):495-503. doi: 10.1007/BF01241206.
10
Specific immunoglobulin responses after varicella and herpes zoster.水痘和带状疱疹后的特异性免疫球蛋白反应。
J Hyg (Lond). 1979 Apr;82(2):319-36. doi: 10.1017/s0022172400025730.