O'Dowd T C, West R R, Ribeiro C D, Smail J E, Munro J A
Br Med J (Clin Res Ed). 1986 Jun 21;292(6536):1640-2. doi: 10.1136/bmj.292.6536.1640.
In a study of 154 adult women who presented to their general practitioner with vaginal symptoms 30 (20%) had Gardnerella vaginalis on its own and 51 (33%) had G vaginalis in combination with anaerobes or known pathogens. Thirty one (20%) patients were culture negative. Those who were culture negative had fewer symptoms and signs of vaginitis than those with G vaginalis alone or G vaginalis plus anaerobes. Those with known pathogens had more symptoms and signs than those with G vaginalis alone or G vaginalis plus anaerobes. Those with known pathogens plus G vaginalis had the most severe signs and symptoms of vaginitis. It is concluded that G vaginalis can cause vaginitis on its own, and it makes vaginitis worse when present with other organisms. G vaginalis was also found in 30 (21%) of the 138 control patients who, although they presented "asymptomatically," had worse signs than control patients without G vaginalis. It seems that G vaginalis can occur in a spectrum ranging from the uncomplaining patient to those with severe vaginitis.
在一项针对154名因阴道症状前来全科医生处就诊的成年女性的研究中，30名（20%）仅感染阴道加德纳菌，51名（33%）感染阴道加德纳菌并伴有厌氧菌或已知病原体。31名（20%）患者培养结果为阴性。培养结果为阴性的患者比仅感染阴道加德纳菌或感染阴道加德纳菌并伴有厌氧菌的患者有更少的阴道炎症状和体征。有已知病原体的患者比仅感染阴道加德纳菌或感染阴道加德纳菌并伴有厌氧菌的患者有更多的症状和体征。有已知病原体且感染阴道加德纳菌的患者有最严重的阴道炎体征和症状。得出的结论是，阴道加德纳菌可单独引起阴道炎，当与其他微生物同时存在时会使阴道炎加重。在138名对照患者中，30名（21%）也发现了阴道加德纳菌，这些对照患者虽然“无症状”，但其体征比没有阴道加德纳菌的对照患者更严重。似乎阴道加德纳菌可出现在从无主诉患者到患有严重阴道炎患者的不同范围内。
