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视网膜植入物阿格斯II型植入后II型Usher综合征的长期视觉结果及康复情况。

Long-term visual outcomes and rehabilitation in Usher syndrome type II after retinal implant Argus II.

作者信息

Nadal Jeroni, Iglesias María

机构信息

Barraquer Opthalmology Centre, International university of Cataluña, Barcelona, Spain.

出版信息

BMC Ophthalmol. 2018 Aug 22;18(1):205. doi: 10.1186/s12886-018-0880-5.

DOI:10.1186/s12886-018-0880-5
PMID:30134849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6103969/
Abstract

BACKGROUND

The aim of this article is to describe visual outcomes and posterior rehabilitation of the first Usher syndrome type II (USH2) patient receiving an Argus II (®) prosthesis.

CASE PRESENTATION

We present a case of a USH2 patient who underwent Argus II prosthesis surgery at the age of 53. He had hearing loss from birth and presented a very poor visual field with good light perception. He communicated through sign language translated by his interpreter, who explained all the information regarding the surgical procedure and who assisted in the posterior visual therapy. Sixteen months after surgery, the patient communicates more fluently with sign language and is able to identify letters with high contrast over 6 cm and words up to four letters.

CONCLUSIONS

This is the first case described in the literature of a USH2 patient receiving an Argus II prosthesis This is an alternative treatment for USH2 patients, whose interpreters are essential in the selection process and subsequent rehabilitation after surgery.

摘要

背景

本文旨在描述首例接受阿格斯II型(®)假体植入的II型Usher综合征(USH2)患者的视觉效果及术后康复情况。

病例报告

我们报告了一例USH2患者,该患者53岁时接受了阿格斯II型假体植入手术。他自出生起就有听力损失,视野非常差,但光感良好。他通过手语交流,由翻译进行翻译,翻译解释了所有关于手术过程的信息,并协助进行术后视觉治疗。术后16个月,患者能用手语更流畅地交流,能够识别对比度高的6厘米以上的字母以及最多四个字母的单词。

结论

这是文献中描述的首例接受阿格斯II型假体植入的USH2患者。这是USH2患者的一种替代治疗方法,其翻译在手术选择过程及后续康复中至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/0fd72b68e211/12886_2018_880_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/32e828c3b36c/12886_2018_880_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/eda89c1cceb9/12886_2018_880_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/906de2fcdb84/12886_2018_880_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/0fd72b68e211/12886_2018_880_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/32e828c3b36c/12886_2018_880_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/eda89c1cceb9/12886_2018_880_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/906de2fcdb84/12886_2018_880_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77bd/6103969/0fd72b68e211/12886_2018_880_Fig4_HTML.jpg

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本文引用的文献

1
Hand-Camera Coordination Varies over Time in Users of the Argus(®) II Retinal Prosthesis System.在阿格斯(®)II视网膜假体系统使用者中,手持相机的协调性随时间变化。
Front Syst Neurosci. 2016 May 6;10:41. doi: 10.3389/fnsys.2016.00041. eCollection 2016.
2
Visual Prognosis in USH2A-Associated Retinitis Pigmentosa Is Worse for Patients with Usher Syndrome Type IIa Than for Those with Nonsyndromic Retinitis Pigmentosa.USH2A 相关性视网膜色素变性的视觉预后对 Usher 综合征 IIa 型患者比非综合征性视网膜色素变性患者更差。
Ophthalmology. 2016 May;123(5):1151-60. doi: 10.1016/j.ophtha.2016.01.021. Epub 2016 Feb 27.
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Use of the Argus II retinal prosthesis to improve visual guidance of fine hand movements.
亚太地区首例遗传性失明眼内植入物。
Hawaii J Health Soc Welf. 2021 Nov;80(11 Suppl 3):10-15.
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Usher syndrome: clinical features, molecular genetics and advancing therapeutics.尤塞氏综合征:临床特征、分子遗传学及治疗进展
Ther Adv Ophthalmol. 2020 Sep 17;12:2515841420952194. doi: 10.1177/2515841420952194. eCollection 2020 Jan-Dec.
使用 Argus II 视网膜假体改善精细手部运动的视觉引导。
Invest Ophthalmol Vis Sci. 2012 Aug 1;53(9):5095-101. doi: 10.1167/iovs.12-9536.
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Blind subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task.植入 Argus II 视网膜假体的盲人受试者能够提高空间运动任务的表现。
Br J Ophthalmol. 2011 Apr;95(4):539-43. doi: 10.1136/bjo.2010.179622. Epub 2010 Sep 29.
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Usher syndrome and cochlear implantation.乌舍尔综合征与人工耳蜗植入
Otol Neurotol. 2003 Mar;24(2):216-21. doi: 10.1097/00129492-200303000-00015.