Lo Kevin Bryan, Papazoglou Anna, Chua Lorayne, Candelario Nellowe
Department of Medicine, Einstein Medical Center, Philadelphia, PA, 19141, USA.
F1000Res. 2018 Apr 30;7:520. doi: 10.12688/f1000research.14758.1. eCollection 2018.
Kikuchi-Fujimoto disease is a form of a benign necrotizing lymphadenitis which is most commonly misdiagnosed as tuberculosis and or lymphoma, usually more common among young adults in Asia. It is a benign disease but can mimic a lot of other disease processes spanning infectious, rheumatologic and even hematologic malignancies. Our patient presented with prolonged fever and lymphadenopathy. Initial considerations were lymphoma and a nonspecific viral infection. A CT scan showed diffuse cervical lymphadenopathy with lacrimal gland involvement. An excisional lymph node biopsy was done which revealed Kikuchi disease. Patient was given steroids with immediate response with defervescence. Kikuchi is a disease with many mimics and a complete workup is needed to exclude serious disease like malignancy.
菊池-藤本病是一种良性坏死性淋巴结炎，最常被误诊为结核病和/或淋巴瘤，在亚洲的年轻人中更为常见。它是一种良性疾病，但可以模仿许多其他疾病过程，包括感染性、风湿性甚至血液系统恶性肿瘤。我们的患者表现为长期发热和淋巴结病。最初考虑为淋巴瘤和非特异性病毒感染。CT扫描显示弥漫性颈部淋巴结病伴泪腺受累。进行了切除性淋巴结活检，结果显示为菊池病。患者接受了类固醇治疗，立即退热。菊池病有许多相似的病症，需要进行全面检查以排除如恶性肿瘤等严重疾病。
