6岁男孩左侧外侧裂周区肿瘤手术中应用经颅磁刺激语言图谱辅助：病例报告
Left perisylvian tumor surgery aided by TMS language mapping in a 6-year-old boy: case report.
作者信息
Rosenstock Tizian, Picht Thomas, Schneider Heike, Koch Arend, Thomale Ulrich-Wilhelm
机构信息
Department of Neurosurgery, Charité - Universitäsmedizin Berlin, corporate member of Freie Universität Berlin, and Berlin Institute of Health, Charité University Medicine, Charitéplatz 1, 10117, Berlin, Germany.
Department of Neuropathology, Charité - Universitäsmedizin Berlin, corporate member of Freie Universität Berlin, and Berlin Institute of Health, Charité University Medicine, Charitéplatz 1, 10117, Berlin, Germany.
出版信息
Childs Nerv Syst. 2019 Jan;35(1):175-181. doi: 10.1007/s00381-018-3944-1. Epub 2018 Aug 22.
BACKGROUND
Awake surgery to preserve language function in young children is challenging, therefore reliable non-invasive work-up of language functional anatomy is needed to preserve language function at any cost. Furthermore, there are obvious limitations of an awake craniotomy with direct stimulation on a child.
CASE REPORT
A 6-year-old boy with a low-grade glioma of the left temporal lobe suffering from epileptic seizures underwent surgery, guided by preoperative transcranial magnetic stimulation (TMS) language mapping and consecutive DTI fiber tracking.
DISCUSSION AND CONCLUSION
We report successful surgery of a language eloquent brain tumor in a young child based on TMS mapping and DTI fiber tracking alone. Surgical treatment of left-sided perisylvian tumors in children is discussed.
背景
在幼儿中进行清醒手术以保留语言功能具有挑战性，因此需要可靠的非侵入性语言功能解剖学检查，不惜一切代价保留语言功能。此外，对儿童进行清醒开颅直接刺激存在明显局限性。
病例报告
一名患有左侧颞叶低级胶质瘤且有癫痫发作的6岁男孩接受了手术，手术由术前经颅磁刺激（TMS）语言映射和连续的弥散张量成像（DTI）纤维追踪引导。
讨论与结论
我们报告了仅基于TMS映射和DTI纤维追踪成功对一名幼儿的语言功能区脑肿瘤进行手术的案例。并对儿童左侧外侧裂周围肿瘤的手术治疗进行了讨论。
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