Nitoi Luciana Carmen, Aspazia Stefan Alina, Ionita C, Andrei Carina, Vulpoi Carmen
Rev Med Chir Soc Med Nat Iasi. 2016 Oct-Dec;120(4):812-17.
This cross-sectional study aimed to determine the relationship between socio-economic status and laboratory values with mental and physical components of QoL (quality of life) in chronic dialysis patients.
254 patients were included in the study and divided into two groups: 243 hemodialysis (HD) patients and 11 peritoneal dialysis (PD) patients. QoL was measured by the Short Form 36(SF-36). Scores for all dimensions are expressed on a 0-100 scale. Higher score indicates better health status. Two more questions related to monthly food expenditure and the presence/or lack of family support were added. Laboratory investigations included the following nutritional parameters: serum albumin and creatinine.
Our study results showed that compared to PD group in HD patients QoL was compromised in all SF-36 subscale except physical functioning, role limitations due to physical functioning and role limitations due to emotional functioning. Also, the presence of supportive family members/ caregivers showed a significant improvement of all QoL scores. HD patients who spend at least 90 euros monthly on groceries/food had higher values of SF-36 items. Better QoL is associated with high pre-dialysis serum creatinine and serum albumin levels.
Future work should incorporate larger and more balanced sample sizes and patient recruitment from multiple dialysis centers to truly capture the variability in patient characteristics.
本横断面研究旨在确定慢性透析患者的社会经济状况和实验室检查结果与生活质量（QoL）的心理和生理组成部分之间的关系。
本研究纳入了254例患者，分为两组：243例血液透析（HD）患者和11例腹膜透析（PD）患者。采用简短健康调查问卷36项（SF-36）对生活质量进行测量。所有维度的得分均以0至100分表示。得分越高表明健康状况越好。另外增加了两个与每月食品支出以及是否有家庭支持相关的问题。实验室检查包括以下营养参数：血清白蛋白和肌酐。
我们的研究结果表明，与PD组相比，HD患者在SF-36所有子量表中的生活质量均受到损害，但身体功能、因身体功能导致的角色受限和因情感功能导致的角色受限除外。此外，有支持性的家庭成员/照顾者可使所有生活质量得分显著提高。每月在食品杂货/食物上花费至少90欧元的HD患者，其SF-36各项得分更高。更好的生活质量与透析前较高的血清肌酐和血清白蛋白水平相关。
未来的研究应纳入更大且更均衡的样本量，并从多个透析中心招募患者，以真正把握患者特征的变异性。
