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眼眶减压手术治疗Graves眼病:不同技术及长期效果的比较

Orbital decompression surgery for the treatment of Graves' ophthalmopathy: comparison of different techniques and long-term results.

作者信息

Cubuk Mehmet Ozgur, Konuk Onur, Unal Mehmet

机构信息

Istanbul Education and Research Hospital, Istanbul 34098, Turkey.

Department of Ophthalmology, Gazi University School of Medicine, Besevler, Ankara 06500, Turkey.

出版信息

Int J Ophthalmol. 2018 Aug 18;11(8):1363-1370. doi: 10.18240/ijo.2018.08.18. eCollection 2018.

Abstract

AIM

To evaluate the long-term results of different orbital decompression techniques performed in patients with Graves' ophthalmopathy (GO).

METHODS

Totally 170 cases with GO underwent orbital decompression between 1994 and 2014. Patients were divided into 4 groups as medial-inferior, medial-lateral (balanced), medial-lateral-inferior, and lateral only according to the applied surgical technique. Surgical indications, regression degrees on Hertel exophthalmometer, new-onset diplopia in the primary gaze and new-onset gaze-evoked diplopia after surgery and visual acuity in cases with dysthyroid optic neuropathy (DON) were compared between different surgical techniques.

RESULTS

The study included 248 eyes of 149 patients. The mean age for surgery was 42.3±13.2y. DON was the surgical indication in 36.6% of cases, and three-wall decompression was the most preferred technique in these cases. All types of surgery significantly decrease the Hertel values (<0.005). Balanced medial-lateral, and only lateral wall decompression caused the lowest rate of postoperative new-onset diplopia in primary gaze. The improvement of visual acuity in patients with DON did not significantly differ between the groups (=0.181).

CONCLUSION

The study show that orbital decompression surgery has safe and effective long term results for functional and cosmetic rehabilitation of GO. It significantly reduces Hertel measurements in disfiguring proptosis and improves visual functions especially in DON cases.

摘要

目的

评估对格雷夫斯眼病(GO)患者采用不同眼眶减压技术的长期效果。

方法

1994年至2014年间,共有170例GO患者接受了眼眶减压手术。根据所应用的手术技术,患者被分为4组:内下组、内外(平衡)组、内下外组和仅外侧组。比较不同手术技术之间的手术指征、Hertel突眼计测量的眼球回退程度、术后原在位新发复视及新发性注视性复视情况,以及甲状腺相关眼病性视神经病变(DON)患者的视力。

结果

该研究纳入了149例患者的248只眼。手术的平均年龄为42.3±13.2岁。36.6%的病例以DON作为手术指征,在这些病例中,三壁减压是最常用的技术。所有类型的手术均显著降低了Hertel值(<0.005)。内外平衡减压和仅外侧壁减压导致原在位术后新发复视的发生率最低。各手术组中DON患者的视力改善情况无显著差异(P=0.181)。

结论

该研究表明,眼眶减压手术对GO的功能和外观恢复具有安全有效的长期效果。它能显著降低眼球突出导致的容貌毁损,尤其在DON病例中能改善视觉功能。

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