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多功能超分子囊泡用于联合光热/光动力/缺氧激活化疗。

Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy.

机构信息

Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China.

出版信息

Chem Commun (Camb). 2018 Sep 11;54(73):10328-10331. doi: 10.1039/c8cc05560b.

Abstract

Multifunctional supramolecular vesicles were constructed by self-assembly of water-soluble pillar[5]arene and near infrared-absorbing guest G. They exhibited remarkable antitumor efficacy through simultaneous combination of photothermal, photodynamic and photodynamic-triggered hypoxia-activated chemotherapy.

摘要

多功能超分子囊泡通过水溶性的[5]轮烷和近红外吸收客体 G 的自组装构建而成。它们通过光热、光动力和光动力触发的缺氧激活化疗的联合作用,表现出显著的抗肿瘤疗效。

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