睡眠障碍与特应性皮炎：双向关联？
Sleep disorders and atopic dermatitis: A 2-way street?
机构信息
Department of Pediatrics, Taipei City Hospital Renai Branch, Taipei, Taiwan; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
出版信息
J Allergy Clin Immunol. 2018 Oct;142(4):1033-1040. doi: 10.1016/j.jaci.2018.08.005. Epub 2018 Aug 23.
Sleep disturbance is very common in patients with atopic dermatitis (AD) and is a major factor leading to impaired quality of life. Sleep disturbance is often viewed as one of the symptoms of AD and one of the measures of disease severity. In this review we describe a variety of sleep disorders associated with AD and a wide range of effect that sleep disorders have on patients with AD. We also discuss our current understanding of the mechanism of sleep disturbance in patients with AD. The relationship between sleep disorders and AD might be bidirectional and could form a vicious cycle. Therefore we suggest viewing sleep disorders as a comorbidity of AD for which regular screening and bidirectional management strategies are indicated, with equal focus on maintaining disease control and implementing specific strategies to improve sleep.
睡眠障碍在特应性皮炎（AD）患者中非常常见，是导致生活质量受损的主要因素之一。睡眠障碍通常被视为 AD 的症状之一，也是疾病严重程度的衡量标准之一。在这篇综述中，我们描述了与 AD 相关的各种睡眠障碍，以及睡眠障碍对 AD 患者的广泛影响。我们还讨论了我们目前对 AD 患者睡眠障碍机制的理解。睡眠障碍与 AD 之间的关系可能是双向的，可能形成恶性循环。因此，我们建议将睡眠障碍视为 AD 的一种合并症，需要定期筛查和双向管理策略，既要关注疾病控制，也要实施特定策略来改善睡眠。
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