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载银纳米粒子的聚乙烯醇-木质素电纺纳米纤维的制备与表征及其抗菌活性。

Synthesis and characterization of silver nanoparticles loaded poly(vinyl alcohol)-lignin electrospun nanofibers and their antimicrobial activity.

机构信息

Department of Biotechnology, National Institute of Technology-Raipur, Raipur 492010, Chhattisgarh, India.

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, Building 220, 2800 Kongens Lyngby, Denmark.

出版信息

Int J Biol Macromol. 2018 Dec;120(Pt A):763-767. doi: 10.1016/j.ijbiomac.2018.08.109. Epub 2018 Aug 23.

Abstract

In the present study, poly(vinyl alcohol) (PVA) - Acacia lignin (PL) nanofiber mats loaded with silver nanoparticles were prepared and characterized. In-situ synthesis of silver nanoparticles was accomplished using alkali lignin extracted from Acacia wood as a reducing agent. Ultrafine nanofiber mats of PL incorporated with silver nanoparticles were fabricated using the electrospinning technique. The fiber morphology of the resultant nanofiber was characterized using scanning electron microscopy. The average diameter of the nanofiber was in the range of 100 to 300 nm. The existence of silver nanoparticles was confirmed by X-ray diffraction analysis. The influence of silver nanoparticles on the polymer structure was investigated by mechanical and thermal properties analysis. The antimicrobial activity of the PL nanofibers containing silver nanoparticles was tested against Bacillus circulans (MTCC 7906) and Escherichia coli (MTCC 739) and showed significant results against both microorganisms. The results revealed that PL nanofiber containing silver nanoparticles may have potential applications as membrane filtration, antimicrobial fabrics and wound dressing material.

摘要

在本研究中,制备并表征了负载银纳米粒子的聚乙烯醇(PVA)-金合欢木质素(PL)纳米纤维垫。采用从金合欢木材中提取的碱木质素作为还原剂,实现了银纳米粒子的原位合成。使用静电纺丝技术制备了掺入银纳米粒子的 PL 超细微纳米纤维垫。使用扫描电子显微镜对所得纳米纤维的纤维形态进行了表征。纳米纤维的平均直径在 100 至 300nm 范围内。通过 X 射线衍射分析证实了银纳米粒子的存在。通过机械和热性能分析研究了银纳米粒子对聚合物结构的影响。测试了含有银纳米粒子的 PL 纳米纤维对藤黄微球菌(MTCC 7906)和大肠杆菌(MTCC 739)的抗菌活性,结果表明对这两种微生物均具有显著效果。结果表明,含有银纳米粒子的 PL 纳米纤维可能在膜过滤、抗菌织物和伤口敷贴材料方面具有应用潜力。

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