Rodrigues Simões Ana Paula, Rossi Feliciano Marcus Antonio, Maronezi Marjury Cristina, Uscategui Ricardo Andres Ramirez, Bartlewski Pawel Mieczyslaw, de Almeida Vivian Tavares, Oh David, do Espírito Santo Silva Paloma, da Silva Liege Cristina Garcia, Russiano Vicente Wilter Ricardo
Department of Animal Reproduction, Faculdade de Ciências Agrárias e Veterinárias - UNESP, Av. Prof. Paulo Donato Castellane S/N, 14884-900, Jaboticabal, SP, Brazil.
Department of Animal Reproduction, Faculdade de Ciências Agrárias e Veterinárias - UNESP, Av. Prof. Paulo Donato Castellane S/N, 14884-900, Jaboticabal, SP, Brazil; Universidade Federal do Recôncavo da Bahia, Rua Rui Barbosa 710, 44380-000, Cruz das Almas, BA, Brazil.
Anim Reprod Sci. 2018 Oct;197:170-176. doi: 10.1016/j.anireprosci.2018.08.025. Epub 2018 Aug 22.
Objective was to evaluate the echotexture and characteristics during terminal development of canine foetal respiratory and hepatic systems through elastographic examinations. Fifteen pregnant bitches were evaluated by ultrasonography twice daily, from the 53rd gestational day until whelping, and images obtained from 120 to 0 h before parturition were analysed. Images of foetal lungs and liver were recorded and then used for computer-assisted analyses to determine quantitative attributes. Acoustic Radiation Force Impulse (ARFI) elastographic of internal organs were classified as 'soft' (white areas) or 'hard' (dark areas) and quantitative analyses determined the mean shear wave velocities (SWV) of foetal lungs and liver. After delivery, canine neonates were clinically evaluated, and their health status was monitored weekly until 60 days post-partum. Sonographic parameters over time were compared by ANOVA and Pearson's correlations were used to determine associations between SWVs and echotextural variables. Foetal lungs and liver had a homogeneous echotexture and pulmonary parenchyma appeared hyperechoic when compared with that of the liver. Mean numerical pixel values (NPVs) of lungs decreased from 120 to 24 h and subsequently increased until parturition (P = 0.04). Lungs and liver mean (± SD) SWVs (0.98 ± 0.12 and 0.84 ± 0.11 m/s, respectively) didn't vary (P > 0.05) over time. Fluctuations in pulmonary NPVs indicated there was a pattern corresponding to structural and functional changes that occur during the terminal stage of pre-natal canine development and hence can be a useful diagnostic tool in veterinary. Foetal lung and liver SWVs were relatively consistent and there was no detectable changes during the pre-partum period for this variable or in echotexture.
目的是通过弹性成像检查评估犬胎儿呼吸和肝脏系统在发育末期的回声纹理和特征。对15只怀孕母犬从妊娠第53天至分娩每天进行两次超声检查，并分析分娩前120至0小时获得的图像。记录胎儿肺和肝脏的图像，然后用于计算机辅助分析以确定定量属性。将内部器官的声辐射力脉冲（ARFI）弹性成像分为“软”（白色区域）或“硬”（深色区域），定量分析确定胎儿肺和肝脏的平均剪切波速度（SWV）。分娩后，对犬新生儿进行临床评估，并每周监测其健康状况直至产后60天。通过方差分析比较随时间变化的超声参数，并使用Pearson相关性分析确定SWV与回声纹理变量之间的关联。胎儿肺和肝脏具有均匀的回声纹理，与肝脏相比，肺实质呈高回声。肺的平均数字像素值（NPV）从120小时降至24小时，随后直至分娩时增加（P = 0.04）。肺和肝脏的平均（±标准差）SWV（分别为0.98±0.12和0.84±0.11 m/s）随时间无变化（P>0.05）。肺NPV的波动表明存在与产前犬发育末期发生的结构和功能变化相对应的模式，因此可成为兽医有用的诊断工具。胎儿肺和肝脏的SWV相对一致，在产前期间该变量或回声纹理均未检测到变化。
