• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

F-FDG PET在一名血清癌胚抗原水平高的小细胞肺癌患者小梁间椎体转移诊断中的价值

The Value of F-FDG PET in the Diagnosis of Intertrabecular Vertebral Metastasis in a Small Cell Lung Cancer Patient with a High Serum CEA Level.

作者信息

Morita Shinichi, Suda Takeshi, Oda Chiyumi, Kobayashi Masaaki, Hoshi Takahiro, Kanefuji Tsutomu, Yagi Kazuyoshi, Hasegawa Go, Terai Shuji

机构信息

Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine Niigata University Hospital, Japan.

Department of Internal Medicine, Niigata Cancer Center Hospital, Japan.

出版信息

Intern Med. 2019 Feb 1;58(3):415-418. doi: 10.2169/internalmedicine.1394-18. Epub 2018 Aug 24.

DOI:10.2169/internalmedicine.1394-18
PMID:30146594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6395140/
Abstract

We encountered a small cell lung cancer (SCLC) patient with intertrabecular vertebral metastasis (IVM). A 59-year-old man was admitted to our hospital with weight loss. F-fluorodeoxyglucose positron emission tomography (FDG PET)-CT demonstrated the uptake of fluorodeoxyglucose in the hilum of the left lung and whole-body bones. Despite intensive support, the patient died within a month. Subsequent autopsy revealed a small lesion consisting of small round cells in the left lung. The cancer cells were found to have spread through the replacement of the bone marrow cells while sparing the trabecular bone. This case demonstrated the potential of F-FDG PET for detecting IVM in SCLC patients.

摘要

我们遇到了一名患有小梁间椎体转移(IVM)的小细胞肺癌(SCLC)患者。一名59岁男性因体重减轻入住我院。氟脱氧葡萄糖正电子发射断层扫描(FDG PET)-CT显示左肺门和全身骨骼摄取氟脱氧葡萄糖。尽管给予了积极支持,患者在一个月内死亡。随后的尸检显示左肺有一个由小圆形细胞组成的小病灶。发现癌细胞通过替代骨髓细胞而扩散,同时小梁骨未受影响。该病例证明了F-FDG PET在检测SCLC患者IVM方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3128/6395140/36629c2c7e2d/1349-7235-58-0415-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3128/6395140/2930fa1990a5/1349-7235-58-0415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3128/6395140/36629c2c7e2d/1349-7235-58-0415-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3128/6395140/2930fa1990a5/1349-7235-58-0415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3128/6395140/36629c2c7e2d/1349-7235-58-0415-g002.jpg

相似文献

1
The Value of F-FDG PET in the Diagnosis of Intertrabecular Vertebral Metastasis in a Small Cell Lung Cancer Patient with a High Serum CEA Level.F-FDG PET在一名血清癌胚抗原水平高的小细胞肺癌患者小梁间椎体转移诊断中的价值
Intern Med. 2019 Feb 1;58(3):415-418. doi: 10.2169/internalmedicine.1394-18. Epub 2018 Aug 24.
2
[Case of renal cell carcinoma with intertrabecular vertebral metastases detected f-18 fluorodeoxyglucose positron emission tomography and MRI].[通过F-18氟脱氧葡萄糖正电子发射断层扫描和磁共振成像检测到伴有小梁间椎体转移的肾细胞癌病例]
Hinyokika Kiyo. 2014 Jan;60(1):29-32.
3
A Case of Massive Bone Metastases From Lung Cancer Detected Only by 18F-FDG PET/CT.肺癌仅通过 18F-FDG PET/CT 发现的大量骨转移病例。
Clin Nucl Med. 2015 Aug;40(8):e411-4. doi: 10.1097/RLU.0000000000000836.
4
[Prognostic value of (18)F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) in extensive-stage small cell lung cancer].[18F-氟脱氧葡萄糖(FDG)正电子发射断层扫描-计算机断层扫描(PET-CT)在广泛期小细胞肺癌中的预后价值]
Zhonghua Zhong Liu Za Zhi. 2017 Nov 23;39(11):828-834. doi: 10.3760/cma.j.issn.0253-3766.2017.11.005.
5
Comparison of diagnostic ability between (99m)Tc-MDP bone scan and (18)F-FDG PET/CT for bone metastasis in patients with small cell lung cancer.(99m)Tc-MDP 骨扫描与(18)F-FDG PET/CT 对小细胞肺癌患者骨转移诊断能力的比较。
Ann Nucl Med. 2012 Oct;26(8):627-33. doi: 10.1007/s12149-012-0622-3. Epub 2012 Jun 24.
6
Prognostic significance of standardised uptake value (SUV ) measured on 18F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with small cell lung cancer.18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描测量的标准化摄取值(SUV)在小细胞肺癌患者中的预后意义
Eur J Cancer Care (Engl). 2017 Sep;26(5). doi: 10.1111/ecc.12485. Epub 2016 Mar 14.
7
Is there any correlation between levels of serum ostepontin, CEA, and FDG uptake in lung cancer patients with bone metastasis?骨转移肺癌患者血清骨桥蛋白水平、癌胚抗原(CEA)水平与氟代脱氧葡萄糖(FDG)摄取之间是否存在相关性?
Rev Esp Med Nucl Imagen Mol. 2016 Mar-Apr;35(2):102-6. doi: 10.1016/j.remn.2015.09.002. Epub 2015 Oct 27.
8
Extra-thoracic tumor burden but not thoracic tumor burden on (18)F-FDG PET/CT is an independent prognostic biomarker for extensive-disease small cell lung cancer.(18)F-FDG PET/CT 上的胸外肿瘤负荷而非胸部肿瘤负荷是广泛期小细胞肺癌的独立预后生物标志物。
Lung Cancer. 2013 Aug;81(2):218-25. doi: 10.1016/j.lungcan.2013.05.001. Epub 2013 May 31.
9
Clinical impact of 18F-FDG-PET in the suspicion of recurrent colorectal cancer based on asymptomatically elevated serum level of carcinoembryonic antigen (CEA) in Taiwan.基于台湾地区无症状性癌胚抗原(CEA)血清水平升高怀疑复发性结直肠癌时18F-FDG-PET的临床影响
Hepatogastroenterology. 2006 May-Jun;53(69):348-50.
10
Application of F-FDG PET/CT in evaluation of curative effect and prognosis for small cell lung cancer.F-FDG PET/CT在小细胞肺癌疗效评估及预后判断中的应用
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Oct 28;45(10):1255-1260. doi: 10.11817/j.issn.1672-7347.2020.190151.

引用本文的文献

1
MRI and FDG PET/CT findings for small cell neuroendocrine carcinoma of the ovary: a case report and literature review.卵巢小细胞神经内分泌癌的MRI及FDG PET/CT表现:1例病例报告及文献复习
BMC Womens Health. 2025 Jul 22;25(1):362. doi: 10.1186/s12905-025-03922-w.
2
Lung Adenocarcinoma with Chronic Lymphocytic Leukemia Mimicking Bone Metastasis.肺腺癌伴慢性淋巴细胞白血病,拟诊骨转移。
Intern Med. 2023 Jun 15;62(12):1801-1806. doi: 10.2169/internalmedicine.0112-22. Epub 2022 Nov 9.
3
Potential factors of cytokeratin fragment 21-1 and cancer embryonic antigen for mediastinal lymph node metastasis in lung cancer.

本文引用的文献

1
Combined small-cell lung carcinoma: An institutional experience.小细胞肺癌合并:机构经验。
Thorac Cancer. 2014 Jan;5(1):57-62. doi: 10.1111/1759-7714.12059. Epub 2014 Jan 2.
2
Increased serum carcinoembryonic antigen level can predict poor survival of patients with small cell lung cancer.血清癌胚抗原水平升高可预测小细胞肺癌患者的生存不良。
Transl Res. 2015 Oct;166(4):355-65. doi: 10.1016/j.trsl.2015.04.005. Epub 2015 Apr 14.
3
The 2015 WHO classification of lung tumors.2015年世界卫生组织肺肿瘤分类
细胞角蛋白片段21-1和癌胚抗原在肺癌纵隔淋巴结转移中的潜在因素。
Front Genet. 2022 Sep 13;13:1009141. doi: 10.3389/fgene.2022.1009141. eCollection 2022.
4
Whole-body MRI: detecting bone metastases from prostate cancer.全身 MRI:检测前列腺癌的骨转移。
Jpn J Radiol. 2022 Mar;40(3):229-244. doi: 10.1007/s11604-021-01205-6. Epub 2021 Oct 25.
5
Clinical Significance of CYFRA21-1, AFP, CA-153, CEA, and CA-199 in the Diagnosis of Lung Cancer Ocular Metastasis in Hypertension Population.CYFRA21-1、甲胎蛋白、CA-153、癌胚抗原及CA-199在高血压人群肺癌眼转移诊断中的临床意义
Front Cardiovasc Med. 2021 Sep 14;8:670594. doi: 10.3389/fcvm.2021.670594. eCollection 2021.
6
Transcatheter Arterial Embolization Using Microspheres for Palliating Pain from Bone Metastasis in a Patient with Cholangiocellular Carcinoma.经导管动脉栓塞术用微球治疗胆管细胞癌患者骨转移疼痛。
Intern Med. 2021 Jan 15;60(2):241-246. doi: 10.2169/internalmedicine.5351-20. Epub 2020 Sep 12.
7
Assessment of Serum Tumor Markers for Predicting Ocular Metastasis in Lung Adenocarcinoma: A Retrospective Study.血清肿瘤标志物评估对肺腺癌眼转移的预测价值:一项回顾性研究。
Dis Markers. 2020 Jun 25;2020:2102158. doi: 10.1155/2020/2102158. eCollection 2020.
8
Surgical Treatment of Spinal Cord Compression Caused by Metastatic Small Cell Lung Cancer: Ten Years of Experience in a Single Center.转移性小细胞肺癌所致脊髓压迫症的外科治疗:单中心十年经验
Cancer Manag Res. 2020 May 19;12:3571-3578. doi: 10.2147/CMAR.S250422. eCollection 2020.
9
CA-125, CA-153, and CYFRA21-1 as clinical indicators in male lung cancer with ocular metastasis.CA-125、CA-153和细胞角蛋白片段21-1作为男性肺癌眼部转移的临床指标。
J Cancer. 2020 Feb 20;11(10):2730-2736. doi: 10.7150/jca.36238. eCollection 2020.
10
Ocular Metastasis in Elderly Lung Cancer Patients: Potential Risk Factors of CA-125, CA-153 and TPSA.老年肺癌患者的眼部转移:CA-125、CA-153和总前列腺特异性抗原的潜在危险因素
Cancer Manag Res. 2020 Mar 10;12:1801-1808. doi: 10.2147/CMAR.S232734. eCollection 2020.
Pathologe. 2014 Nov;35 Suppl 2:188. doi: 10.1007/s00292-014-1974-3.
4
Survival and prognostic factors in small cell lung cancer.小细胞肺癌的生存和预后因素。
Med Oncol. 2010 Mar;27(1):73-81. doi: 10.1007/s12032-009-9174-3. Epub 2009 Feb 12.
5
Randomised phase III trial of carboplatin plus etoposide vs split doses of cisplatin plus etoposide in elderly or poor-risk patients with extensive disease small-cell lung cancer: JCOG 9702.卡铂联合依托泊苷与分剂量顺铂联合依托泊苷用于老年或预后不良的广泛期小细胞肺癌患者的随机III期试验:JCOG 9702
Br J Cancer. 2007 Jul 16;97(2):162-9. doi: 10.1038/sj.bjc.6603810. Epub 2007 Jun 19.
6
Evaluation of 18F-FDG PET in patients with advanced, metastatic, or recurrent gastric cancer.18F-FDG PET在晚期、转移性或复发性胃癌患者中的评估。
J Nucl Med. 2003 May;44(5):690-9.
7
Small cell lung carcinoma (SCLC): a clinicopathologic study of 100 cases with surgical specimens.小细胞肺癌(SCLC):100例手术标本的临床病理研究
Am J Surg Pathol. 2002 Sep;26(9):1184-97. doi: 10.1097/00000478-200209000-00009.
8
Intertrabecular vertebral metastases: metastases only detectable on MR imaging.小梁间椎体转移瘤:仅在磁共振成像上可检测到的转移瘤。
Semin Musculoskelet Radiol. 2001 Jun;5(2):171-5. doi: 10.1055/s-2001-15676.
9
The skeletal metastatic complications of renal cell carcinoma.肾细胞癌的骨骼转移并发症。
Int J Oncol. 2001 Aug;19(2):379-82. doi: 10.3892/ijo.19.2.379.
10
Surgery for combined type small cell lung carcinoma.复合型小细胞肺癌的手术治疗
Thorax. 1998 Jun;53(6):450-3. doi: 10.1136/thx.53.6.450.