单纯疱疹病毒DNA近端内部重复序列（IRL）中的序列可与人类DNA杂交。
Sequences in the proximal IRL of herpes simplex virus DNA hybridize to human DNA.
作者信息
Jones T R, Hyman R W
出版信息
Virus Res. 1986 Jun;4(4):369-75. doi: 10.1016/0168-1702(86)90083-3.
PMID:3014783
Abstract
A short segment of the herpes simplex virus (HSV) DNA proximal IRL region hybridized to two doublet bands of EcoRI-digested human cellular DNA. The hybridization was abolished neither by increasing stringency conditions nor by inclusion of guanine-rich DNA in the hybridization mixture. Thus, the hybridization appeared to represent authentic base sequence homology between HSV DNA and middle repetitive human DNA.
摘要
单纯疱疹病毒（HSV）DNA近端内部重复序列（IRL）区域的一小段与经EcoRI酶切的人类细胞DNA的两条双峰带杂交。无论是提高严谨性条件，还是在杂交混合物中加入富含鸟嘌呤的DNA，杂交都不会被消除。因此，这种杂交似乎代表了HSV DNA与人类中度重复DNA之间真实的碱基序列同源性。
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