Dal Bo Zanon R, Vicarioto M, Girolami A, De Rossi A, Del Mistro A R, Chieco-Bianchi L
Acta Haematol. 1986;75(1):34-7. doi: 10.1159/000206077.
The first fatal case of AIDS in an hemophiliac observed in Italy is reported. The propositus is a 53-year-old hemophilia A patient who died on the 8th December, 1984. AIDS was documented clinically and in the laboratory by serum antibodies to HTLV-III detected by ELISA and Western blot assays. A progressive intellectual worsening of the patient due to diffuse cerebral atrophy was followed by CT scan, EEG and by evaluation of proper neurological signs and symptoms.
本文报道了在意大利观察到的首例血友病患者艾滋病死亡病例。患者为一名53岁的甲型血友病患者，于1984年12月8日死亡。通过ELISA和蛋白质印迹法检测血清中抗HTLV-III抗体，从临床和实验室方面确诊为艾滋病。通过CT扫描、脑电图以及对相关神经体征和症状的评估，发现患者因弥漫性脑萎缩而出现进行性智力衰退。
