Egal Axel, Ram-Wolf Caroline, Quero Laurent, Bagot Martine, Vignon-Pennamen Marie-Dominique, Hennequin Christophe, M'Barek Basma
Department of Radiotherapy, Montfermeil Hospital, France.
Department of Dermatology, Saint Louis Hospital, AP-HP, Paris, France.
Case Rep Dermatol Med. 2018 Jul 26;2018:1762050. doi: 10.1155/2018/1762050. eCollection 2018.
Mycosis Fungoides (MF) is a rare disease with a relatively good prognosis at early stage. However, skin lesions can impair quality of life due to extensive skin lesions. In some cases, skin lesions, and especially those of the face, become visible and change the physical appearance of the patients. This aspect can deeply affect patients psychologically and can impact their social life. Here, we report the case of a patient with multiple lesions including a disfiguring lesion arising from the nose. The extent of his skin lesions gave a palliative intent to his treatment project. The patient underwent several lines of chemotherapy and immunotherapy with poor results. He was then referred to our radiotherapy and received localized radiotherapy. Lesions disappeared completely within a few weeks. The patient reported a psychological relief. This case highlights the fact that radiotherapy can be done in a "palliative" intent in order to improve esthetic aspects of lesions that can dramatically impact the psychosocial side of patient's life. Clinicians can consider radiotherapy as treatment of some MF lesions as far as they impair the patient's comfort from a psychological and social point of view.
蕈样肉芽肿（MF）是一种罕见疾病，早期预后相对较好。然而，由于广泛的皮肤病变，皮肤损害会影响生活质量。在某些情况下，皮肤病变，尤其是面部病变会变得明显，改变患者的外貌。这方面会在心理上深深影响患者，并可能影响其社交生活。在此，我们报告一例患有多处病变的患者，其中包括一处源于鼻子的毁容性病变。其皮肤病变的程度使其治疗方案具有姑息治疗的意图。该患者接受了多线化疗和免疫治疗，但效果不佳。随后他被转诊至我们科室接受放疗，并接受了局部放疗。病变在几周内完全消失。患者称心理上得到了缓解。该病例突出了这样一个事实，即放疗可以以“姑息”为目的进行，以改善那些会极大影响患者生活心理社会层面的病变的美观问题。只要从心理和社会角度损害了患者的舒适度，临床医生就可以将放疗视为某些蕈样肉芽肿病变的治疗方法。
