Rosen P P
Am J Surg Pathol. 1986 Jul;10(7):464-9. doi: 10.1097/00000478-198607000-00003.
Ruptured cysts of the breast containing mucinous material may discharge secretions and epithelium into the surrounding tissues. This is a benign, little-known condition analogous to mucocele of the minor salivary glands. The age at diagnosis of six women with mucocele-like lesions (MLL) of the breast averaged 40 years (range, 25-61) and all but one were premenopausal. The lesion caused a mass in five cases. In one it was an incidental finding, and this patient had a separate unrelated nonmucinous intraductal carcinoma treated by mastectomy. One woman was treated by simple mastectomy. Four patients were treated by excision. All have remained well with follow-up of 6-88 months. The histological appearance of MLL of the breast simulates colloid carcinoma and should be considered in the differential diagnosis of such lesions. This is particularly important in young, premenopausal women, among whom colloid carcinoma is very uncommon. The contents of mammary MLL may be difficult to distinguish from colloid carcinoma in an aspiration biopsy.
含有黏液性物质的乳腺破裂囊肿可将分泌物和上皮细胞排入周围组织。这是一种良性的、鲜为人知的病症,类似于小唾液腺黏液囊肿。6例乳腺黏液囊肿样病变(MLL)患者的诊断年龄平均为40岁(范围25 - 61岁),除1例之外均为绝经前患者。该病变在5例中导致肿块形成。1例为偶然发现,该患者另有1例与之无关的非黏液性导管内癌,接受了乳房切除术。1名女性接受了单纯乳房切除术。4例患者接受了切除术。所有患者在6 - 88个月的随访中情况良好。乳腺MLL的组织学表现类似于胶样癌,在对此类病变进行鉴别诊断时应予以考虑。这在年轻的绝经前女性中尤为重要,因为胶样癌在她们当中非常罕见。在针吸活检中,乳腺MLL的内容物可能难以与胶样癌区分开来。