Brasiliense Danielle Murici, Lima Karla Valéria Batista, Pérez-Chaparro Paula Juliana, Mamizuka Elsa Masae, de Oliveira Souza Cintya, Dutra Livia Maria Guimarães, McCulloch John Anthony
Laboratório de Biologia Molecular, Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, Ananindeua-PA, Brazil.
Laboratório de Biologia Molecular, Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, Ananindeua-PA, Brazil.
Diagn Microbiol Infect Dis. 2019 Jan;93(1):82-84. doi: 10.1016/j.diagmicrobio.2018.07.017. Epub 2018 Aug 1.
We sought to characterize the genetic context of bla gene in a carbapenem-resistant Acinetobacter pittii strain recovered from a hospitalized patient from Belém, North Brazil, in the Amazon region. We found that the bla gene was carried by a small plasmid, pIEC338SCox, that is 10,498 bp. The gene is flanked by XerC/XerD-like recombinase sites, which suggests that this gene was acquired onto this plasmid by recombination.
我们试图对从巴西北部贝伦市一名住院患者身上分离出的一株耐碳青霉烯类鲍氏不动杆菌菌株中的bla基因的遗传背景进行表征。该患者位于亚马逊地区。我们发现bla基因由一个10498 bp的小质粒pIEC338SCox携带。该基因两侧是XerC/XerD样重组酶位点，这表明该基因是通过重组获得到这个质粒上的。
