Teng Yunjie, Wang Shuxia, Wang Ning
Center of Health Management, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, China.
Department of No. 1 Cadre Ward Medicine, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, China.
Arch Med Sci. 2018 Aug;14(5):971-978. doi: 10.5114/aoms.2018.73984. Epub 2018 Mar 2.
The aim of the current study was to evaluate the efficiency of the STOP-Bang questionnaire for obstructive sleep apnea (OSA) screening among Chinese patients with type 2 diabetes mellitus (T2DM).
A total of 262 patients with T2DM were enrolled for STOP-Bang questionnaire evaluation and polysomnography (PSG) monitoring between May 2015 and September 2016. Patients were divided into non-OSA and different OSA severity groups (mild, moderate, and severe) according to the apnea-hypopnea index (AHI). The value of the STOP-Bang questionnaire for OSA screening was evaluated.
Efficiency of the STOP-Bang questionnaire for OSA screening among Chinese patients with T2DM was as follows: when AHI ≥ 5/h, the area under the curve (AUC) was 0.825 (95% confidence interval (CI): 0.763-0.887, < 0.05), sensitivity was 85.6% (95% CI: 85.55-85.65%, < 0.05) and specificity was 60% (95% CI: 59.85-60.15%, < 0.05); when AHI > 15/h, the AUC was 0.856 (95% CI: 0.799-0.913, < 0.05), sensitivity was 88.6% (95% CI: 88.55-88.65%, < 0.05) and specificity was 38.4% (95% CI: 38.30-38.49%, < 0.05); when AHI > 30/h, the AUC was 0.891 (95% CI: 0.836-0.946, < 0.05), sensitivity was 90.5% (95% CI: 90.44-90.56%, < 0.05), and specificity was 27% (95% CI: 26.94-27.07%, < 0.05).
The STOP-Bang questionnaire is an effective tool for OSA screening among Chinese patients with T2DM. A cut-off score of 3 distinguishes OSA from non-OSA with high sensitivity.
本研究旨在评估STOP-Bang问卷在中国2型糖尿病（T2DM）患者中筛查阻塞性睡眠呼吸暂停（OSA）的效率。
2015年5月至2016年9月期间，共纳入262例T2DM患者进行STOP-Bang问卷评估和多导睡眠图（PSG）监测。根据呼吸暂停低通气指数（AHI）将患者分为非OSA组和不同OSA严重程度组（轻度、中度和重度）。评估STOP-Bang问卷对OSA筛查的价值。
STOP-Bang问卷在中国T2DM患者中筛查OSA的效率如下：当AHI≥5/h时，曲线下面积（AUC）为0.825（95%置信区间（CI）：0.763 - 0.887，P<0.05），敏感性为85.6%（95%CI：85.55 - 85.65%，P<0.05），特异性为60%（95%CI：59.85 - 60.15%，P<0.05）；当AHI>15/h时，AUC为0.856（95%CI：0.799 - 0.913，P<0.05），敏感性为88.6%（95%CI：88.55 - 88.65%，P<0.05），特异性为38.4%（95%CI：38.30 - 38.49%，P<0.05）；当AHI>30/h时，AUC为0.891（95%CI：0.836 - 0.946，P<0.05），敏感性为90.5%（95%CI：90.44 - 90.56%，P<0.05），特异性为27%（95%CI：26.94 - 27.07%，P<0.05）。
STOP-Bang问卷是在中国T2DM患者中筛查OSA的有效工具。截断分数为3时，能以高敏感性区分OSA与非OSA。
