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STOP-Bang问卷在睡眠临床环境中对肥胖人群阻塞性睡眠呼吸暂停筛查的预测性能。

The Predictive Performance of the STOP-Bang Questionnaire in Obstructive Sleep Apnea Screening of Obese Population at Sleep Clinical Setting.

作者信息

Mergen Haluk, Altındağ Burak, Zeren Uçar Zeynep, Karasu Kılıçaslan Işıl

机构信息

Family Medicine, University of Health Sciences, Izmir Tepecik Health Practice & Research Center, Izmir, TUR.

Sleep Medicine, University of Health Sciences, Izmir Dr. Suat Seren Health Practice & Research Center, Izmir, TUR.

出版信息

Cureus. 2019 Dec 29;11(12):e6498. doi: 10.7759/cureus.6498.

Abstract

Background The prevalence of obstructive sleep apnea (OSA) is high in the obese population. In this study, it was aimed to fulfill the STOP-Bang questionnaire which is a concise and easy-to-use questionnaire for OSA screening in obese patients. Materials & methods This is a retrospective study where the patients, who planned polysomnography, were referred to sleep clinic. Patients were screened for OSA by the STOP-Bang questionnaire. Laboratory polysomnography was performed in 275 patients. Patients with BMI ≥ 30 were taken into study. The screening test was evaluated by three different risk analysis such as, a STOP score, a STOP-Bang score and a modified STOP-Bang score. The predictive parameters (sensitivity, specificity, and positive and negative predictive values) for alternative scoring models in obese patients were analyzed. Results In 217 obese patients, a STOP score cutoff of 3 and a STOP-Bang score cutoff of 4 provides a better balance of sensitivity and specificity for all OSA (apnea-hypopnea index [AHI] ≥ 5). The STOP questionnaire revealed a sensitivity of 87.9% and a positive predictive value of 99.5% for patients with all OSA (p: 0.005). The STOP-Bang scoring model revealed a sensitivity of 95.3% and a positive predictive value of 99.5% for patients with all OSA (p < 0.001). The modified STOP-Bang scoring revealed a sensitivity of 95.8% and a positive predictive value of 99.5% for patients with all OSA (p < 0.001). The area under the curve of the STOP-Bang for identifying mild, moderate and severe OSA was 0.581, 0.652 and 0.675, respectively. Whereas according to the STOP-Bang, all morbid obese patients (obesity class III, n: 47) were at high risk of OSA. Conclusion This study suggests that the STOP-Bang questionnaire for obstructive sleep apnea screening in obese patients is a high sensitivity and appropriate screening test.

摘要

背景

肥胖人群中阻塞性睡眠呼吸暂停(OSA)的患病率很高。本研究旨在完成STOP-Bang问卷,这是一种用于肥胖患者OSA筛查的简洁易用的问卷。

材料与方法

这是一项回顾性研究,计划进行多导睡眠图检查的患者被转诊至睡眠诊所。通过STOP-Bang问卷对患者进行OSA筛查。对275例患者进行了实验室多导睡眠图检查。纳入研究的患者BMI≥30。通过三种不同的风险分析评估筛查试验,即STOP评分、STOP-Bang评分和改良STOP-Bang评分。分析了肥胖患者替代评分模型的预测参数(敏感性、特异性以及阳性和阴性预测值)。

结果

在217例肥胖患者中,STOP评分临界值为3且STOP-Bang评分临界值为4时,对所有OSA(呼吸暂停低通气指数[AHI]≥5)而言,敏感性和特异性的平衡更佳。STOP问卷显示,所有OSA患者的敏感性为87.9%,阳性预测值为99.5%(p:0.005)。STOP-Bang评分模型显示,所有OSA患者的敏感性为95.3%,阳性预测值为99.5%(p<0.001)。改良STOP-Bang评分显示,所有OSA患者的敏感性为95.8%,阳性预测值为99.5%(p<0.001)。用于识别轻度、中度和重度OSA的STOP-Bang曲线下面积分别为0.581、0.652和0.675。而根据STOP-Bang问卷,所有病态肥胖患者(III级肥胖,n:47)均处于OSA高风险。

结论

本研究表明,用于肥胖患者阻塞性睡眠呼吸暂停筛查的STOP-Bang问卷是一种高敏感性且合适的筛查试验。

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