• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

糖尿病患者初级保健多学科风险评估和管理方案(RAMP-DM)的终生成本效益分析。

Cost-effectiveness of a primary care multidisciplinary Risk Assessment and Management Program for patients with diabetes mellitus (RAMP-DM) over lifetime.

机构信息

Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F., 161 Main Street, Ap Lei Chau Clinic, Ap Lei Chau, Hong Kong, Hong Kong.

School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 5/F, William MW Mong Block, 21 Sassoon Road, Hong Kong, Hong Kong.

出版信息

Endocrine. 2019 Feb;63(2):259-269. doi: 10.1007/s12020-018-1727-9. Epub 2018 Aug 28.

DOI:10.1007/s12020-018-1727-9
PMID:30155847
Abstract

PURPOSE

The multidisciplinary Risk Assessment and Management Program for patients with diabetes mellitus (RAMP-DM) was found to be cost-saving in comparison with usual primary care over 5 years' follow-up. This study aimed to estimate the cost-effectiveness of RAMP-DM over lifetime.

METHODS

We built a Discrete Event Simulation model to evaluate the cost-effectiveness of RAMP-DM over lifespan from public health service provider's perspective. Transition probabilities among disease states were extrapolated from a cohort of 17,140 propensity score matched participants in RAMP-DM and those under usual primary care over 5-year's follow-up. The mortality of patients with specific DM-related complications was estimated from a cohort of 206,238 patients with diabetes. Health preference and direct medical costs of DM patients referred to our previous studies among Chinese DM patients.

RESULTS

RAMP-DM individuals gained 0.745 QALYs and cost US$1404 less than those under usual care. The probabilistic sensitivity analysis found that RAMP-DM had 86.0% chance of being cost-saving compared to usual care under the assumptions and estimates used in the model. The probability of RAMP-DM being cost-effective compared to usual care would be over 99%, when the willingness to pay threshold is HK$20,000 (US$ 2564) or higher.

CONCLUSION

RAMP-DM added to usual primary care was cost-saving in managing people with diabetes over lifetime. These findings support the integration of RAMP-DM as part of routine primary care for all patients with diabetes.

摘要

目的

与 5 年随访期间的常规初级保健相比,多学科糖尿病患者风险评估和管理计划(RAMP-DM)被发现具有成本效益。本研究旨在估计 RAMP-DM 在终身内的成本效益。

方法

我们构建了一个离散事件模拟模型,从公共卫生服务提供者的角度评估 RAMP-DM 在寿命期间的成本效益。疾病状态之间的转移概率是从 RAMP-DM 中 17140 名倾向评分匹配参与者和 5 年随访期间常规初级保健下的参与者队列中推断出来的。特定糖尿病相关并发症患者的死亡率是从 206238 名糖尿病患者的队列中估计出来的。健康偏好和我们之前在中国糖尿病患者研究中引用的糖尿病患者的直接医疗费用。

结果

RAMP-DM 个体获得了 0.745 个 QALYs,比常规护理组节省了 1404 美元。概率敏感性分析发现,在模型中使用的假设和估计下,RAMP-DM 与常规护理相比,有 86.0%的可能性具有成本效益。当支付意愿阈值为 20000 港元(2564 美元)或更高时,RAMP-DM 比常规护理更具成本效益的概率将超过 99%。

结论

在管理糖尿病患者的终身中,将 RAMP-DM 添加到常规初级保健中具有成本效益。这些发现支持将 RAMP-DM 整合为所有糖尿病患者常规初级保健的一部分。

相似文献

1
Cost-effectiveness of a primary care multidisciplinary Risk Assessment and Management Program for patients with diabetes mellitus (RAMP-DM) over lifetime.糖尿病患者初级保健多学科风险评估和管理方案(RAMP-DM)的终生成本效益分析。
Endocrine. 2019 Feb;63(2):259-269. doi: 10.1007/s12020-018-1727-9. Epub 2018 Aug 28.
2
Five-Year Cost-effectiveness of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM).多学科风险评估和管理计划-糖尿病(RAMP-DM)的五年成本效益。
Diabetes Care. 2018 Feb;41(2):250-257. doi: 10.2337/dc17-1149. Epub 2017 Dec 15.
3
Long-term effects of the multidisciplinary risk assessment and management program for patients with diabetes mellitus (RAMP-DM): a population-based cohort study.糖尿病患者多学科风险评估与管理项目(RAMP-DM)的长期影响:一项基于人群的队列研究。
Cardiovasc Diabetol. 2015 Aug 14;14:105. doi: 10.1186/s12933-015-0267-3.
4
Five-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM) on Diabetes-Related Complications and Health Service Uses-A Population-Based and Propensity-Matched Cohort Study.基于人群和倾向匹配队列研究:多学科风险评估和管理方案-糖尿病(RAMP-DM)对糖尿病相关并发症和卫生服务利用的 5 年效果。
Diabetes Care. 2018 Jan;41(1):49-59. doi: 10.2337/dc17-0426. Epub 2017 Nov 14.
5
Ten-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM) on Macrovascular and Microvascular Complications and All-Cause Mortality: A Population-Based Cohort Study.十年多学科风险评估和管理计划-糖尿病(RAMP-DM)对大血管和微血管并发症及全因死亡率的影响:一项基于人群的队列研究。
Diabetes Care. 2022 Dec 1;45(12):2871-2882. doi: 10.2337/dc22-0387.
6
Long-term cost-effectiveness of a Patient Empowerment Programme for type 2 diabetes mellitus in primary care.患者授权计划在初级保健中对 2 型糖尿病的长期成本效益分析。
Diabetes Obes Metab. 2019 Jan;21(1):73-83. doi: 10.1111/dom.13485. Epub 2018 Sep 4.
7
Effects of the Multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) on biomedical outcomes, observed cardiovascular events and cardiovascular risks in primary care: a longitudinal comparative study.糖尿病患者多学科风险评估与管理项目(RAMP-DM)对基层医疗中生物医学结局、观察到的心血管事件及心血管风险的影响:一项纵向比较研究。
Cardiovasc Diabetol. 2014 Aug 21;13:127. doi: 10.1186/s12933-014-0127-6.
8
Risk of Dementia Among Patients With Diabetes in a Multidisciplinary, Primary Care Management Program.多学科、初级保健管理计划中糖尿病患者的痴呆风险。
JAMA Netw Open. 2024 Feb 5;7(2):e2355733. doi: 10.1001/jamanetworkopen.2023.55733.
9
Effectiveness of the multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) for diabetic microvascular complications: A population-based cohort study.糖尿病微血管并发症多学科风险评估与管理项目(RAMP-DM)对糖尿病患者的有效性:一项基于人群的队列研究。
Diabetes Metab. 2016 Dec;42(6):424-432. doi: 10.1016/j.diabet.2016.07.030. Epub 2016 Aug 24.
10
Effectiveness of a multidisciplinary risk assessment and management programme-diabetes mellitus (RAMP-DM) on patient-reported outcomes.多学科风险评估与管理项目——糖尿病(RAMP-DM)对患者报告结局的有效性。
Endocrine. 2017 Feb;55(2):416-426. doi: 10.1007/s12020-016-1124-1. Epub 2016 Oct 3.

引用本文的文献

1
Evaluation of the effectiveness and cost-effectiveness of the chronic disease co-care (CDCC) Pilot Scheme: a study protocol.慢性病联合照护(CDCC)试点计划的有效性和成本效益评估:一项研究方案
BMC Prim Care. 2025 Mar 19;26(1):73. doi: 10.1186/s12875-025-02765-6.
2
Prediction of complications in health economic models of type 2 diabetes: a review of methods used.预测 2 型糖尿病健康经济模型中的并发症:方法综述。
Acta Diabetol. 2023 Jul;60(7):861-879. doi: 10.1007/s00592-023-02045-8. Epub 2023 Mar 3.
3
Long-term spill-over impact of COVID-19 on health and healthcare of people with non-communicable diseases: a study protocol for a population-based cohort and health economic study.

本文引用的文献

1
Five-Year Cost-effectiveness of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM).多学科风险评估和管理计划-糖尿病(RAMP-DM)的五年成本效益。
Diabetes Care. 2018 Feb;41(2):250-257. doi: 10.2337/dc17-1149. Epub 2017 Dec 15.
2
Five-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM) on Diabetes-Related Complications and Health Service Uses-A Population-Based and Propensity-Matched Cohort Study.基于人群和倾向匹配队列研究:多学科风险评估和管理方案-糖尿病(RAMP-DM)对糖尿病相关并发症和卫生服务利用的 5 年效果。
Diabetes Care. 2018 Jan;41(1):49-59. doi: 10.2337/dc17-0426. Epub 2017 Nov 14.
3
《COVID-19 对患有非传染性疾病人群的健康和医疗保健的长期溢出影响:一项基于人群的队列研究和健康经济学研究方案》
BMJ Open. 2022 Aug 16;12(8):e063150. doi: 10.1136/bmjopen-2022-063150.
4
How to Address Uncertainty in Health Economic Discrete-Event Simulation Models: An Illustration for Chronic Obstructive Pulmonary Disease.如何解决健康经济离散事件模拟模型中的不确定性:以慢性阻塞性肺疾病为例。
Med Decis Making. 2020 Jul;40(5):619-632. doi: 10.1177/0272989X20932145. Epub 2020 Jul 1.
Annual direct medical costs associated with diabetes-related complications in the event year and in subsequent years in Hong Kong.
香港与糖尿病相关并发症有关的年度直接医疗费用,包括当年及随后几年的费用。
Diabet Med. 2017 Sep;34(9):1276-1283. doi: 10.1111/dme.13416. Epub 2017 Jul 12.
4
Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: decrements associated with individual complication and number of complications.在初级保健和二级保健环境中接受治疗的中国糖尿病患者的健康相关生活质量和健康偏好:与个体并发症及并发症数量相关的健康状况下降。
Health Qual Life Outcomes. 2017 Jun 13;15(1):125. doi: 10.1186/s12955-017-0699-4.
5
Effectiveness of the multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) for diabetic microvascular complications: A population-based cohort study.糖尿病微血管并发症多学科风险评估与管理项目(RAMP-DM)对糖尿病患者的有效性:一项基于人群的队列研究。
Diabetes Metab. 2016 Dec;42(6):424-432. doi: 10.1016/j.diabet.2016.07.030. Epub 2016 Aug 24.
6
Severe Hypoglycemia and Cardiovascular or All-Cause Mortality in Patients with Type 2 Diabetes.2型糖尿病患者的严重低血糖与心血管疾病或全因死亡率
Diabetes Metab J. 2016 Jun;40(3):202-10. doi: 10.4093/dmj.2016.40.3.202. Epub 2016 Apr 21.
7
Long-term effects of the multidisciplinary risk assessment and management program for patients with diabetes mellitus (RAMP-DM): a population-based cohort study.糖尿病患者多学科风险评估与管理项目(RAMP-DM)的长期影响:一项基于人群的队列研究。
Cardiovasc Diabetol. 2015 Aug 14;14:105. doi: 10.1186/s12933-015-0267-3.
8
Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship.休闲时间身体活动与死亡率:剂量反应关系的详细汇总分析
JAMA Intern Med. 2015 Jun;175(6):959-67. doi: 10.1001/jamainternmed.2015.0533.
9
Cost-effectiveness of intensive multifactorial treatment compared with routine care for individuals with screen-detected Type 2 diabetes: analysis of the ADDITION-UK cluster-randomized controlled trial.与常规护理相比,强化多因素治疗对筛查发现的2型糖尿病患者的成本效益:英国ADDITION集群随机对照试验分析
Diabet Med. 2015 Jul;32(7):907-19. doi: 10.1111/dme.12711. Epub 2015 Apr 15.
10
Comparison of four cardiovascular risk prediction functions among Chinese patients with diabetes mellitus in the primary care setting.基层医疗环境中中国糖尿病患者四种心血管疾病风险预测功能的比较。
J Diabetes Investig. 2014 Sep;5(5):606-14. doi: 10.1111/jdi.12188. Epub 2014 Feb 11.