von Heijne G
EMBO J. 1986 Jun;5(6):1335-42. doi: 10.1002/j.1460-2075.1986.tb04364.x.
Twenty three mitochondrial targeting sequences have been analysed with regard to their potential for forming amphiphilic helices. It is shown that most if not all of these sequences can be expected to form helices with high hydrophobic moments in a suitable environment. In the few cases studied so far, the segments of maximal hydrophobic moment coincide closely with 'critical' regions defined by deletions and point mutations.
对23个线粒体靶向序列形成两亲性螺旋的潜力进行了分析。结果表明，这些序列中的大多数（如果不是全部的话）在合适的环境中有望形成具有高疏水矩的螺旋。在目前研究的少数案例中，最大疏水矩的片段与由缺失和点突变定义的“关键”区域紧密重合。
