Suh Minhee
J Neurosci Nurs. 2018 Oct;50(5):279-285. doi: 10.1097/JNN.0000000000000394.
This study investigated the level of cortisol under different stressful situations and its relationship with sleep and anxiety in female college students.
Salivary cortisol was measured 6 times a day during a routine period free of examination stress and a stressful period. Area under the curve (AUC) was calculated for cortisol level for awakening response (AUCAG) and during the day (AUCTG). Sleep characteristics and anxiety were measured using an actigraph and the Spielberger State-Trait Anxiety Inventory, respectively, during the different periods.
Thirty-six people participated in the study. During the stressful period, anxiety had a positive correlation with sleep efficiency (P = .020), wake after sleep onset (P = .023), and mean wake episodes during sleep (P = .048). Poorer sleep efficiency (P = .014), greater wake after sleep onset (P = .008), and mean wake episodes during sleep (P = .044) were significantly associated with less AUCAG. Trait anxiety was significantly higher in participants with greater AUCTG (P = .008).
Female college students with increased anxiety under the stressful situation slept better. Those with poor sleep showed attenuated morning cortisol secretion. Those with higher trait anxiety had greater cortisol during the day.
本研究调查了女大学生在不同应激情况下的皮质醇水平及其与睡眠和焦虑的关系。
在无考试压力的常规时期和应激时期，每天测量6次唾液皮质醇。计算觉醒反应时皮质醇水平的曲线下面积（AUCAG）和白天的曲线下面积（AUCTG）。在不同时期，分别使用活动记录仪和斯皮尔伯格状态-特质焦虑量表测量睡眠特征和焦虑情况。
36人参与了该研究。在应激时期，焦虑与睡眠效率（P = 0.020）、入睡后觉醒（P = 0.023）以及睡眠期间平均觉醒次数（P = 0.048）呈正相关。较差的睡眠效率（P = 0.014）、较高的入睡后觉醒（P = 0.008）以及睡眠期间平均觉醒次数（P = 0.044）与较低的AUCAG显著相关。AUCTG较高的参与者特质焦虑显著更高（P = 0.008）。
处于应激状态下焦虑增加的女大学生睡眠更好。睡眠不佳的学生早晨皮质醇分泌减弱。特质焦虑较高的学生白天皮质醇水平更高。
