Xie Xiaoyuan, Wang Yaning, Zeng Qingting, Lv Ying, Hu Rong, Zhu Ke, Liu Chen, Lai Wei, Guan Lei
Department of Dermatology and Venereology, The 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Skin Research Center, Landproof Testing Technology Co., Ltd, Guangzhou, China.
J Cosmet Dermatol. 2018 Oct;17(5):935-944. doi: 10.1111/jocd.12762. Epub 2018 Aug 29.
Neck skin aging is of particular interest to skin scientists and dermatologists because of the increasing demand for neck wrinkle improvement. This study aimed to determine the neck aging features of Chinese women and to investigate the clinical alterations and mechanical, topographical, and biophysical properties of neck skin.
A total of 450 Chinese women (age range: 16-66 years) were clinically examined and graded by the same dermatologist using standardized photographs. The skin properties were assessed by noninvasive skin measuring devices.
The results showed that different neck aging signs, including the horizontal neck fold, neck sagging, hollowing of emaciated neck, platysmal bands, and neck texture, appeared in different ages, and all of them worsened age-dependently since they manifested. The skin elasticity markedly changed before the onset of most of the aging signs and showed a negative correlation with both age and the severity of these signs. Transepidermal water loss (TEWL) was positively correlated with age, whereas hydration and pH were not significantly correlated with age. We also found that wrinkles (SEw) and average roughness (Ra) were significantly correlated with age. SEw, smoothness, the average depth of roughness (Rz), TEWL, and erythema index were significantly and positively correlated with the severity of the horizontal neck fold, neck sagging, hollowing of emaciated neck, and platysmal bands.
This is the first study to emphasize that age causes diverse changes in Chinese women's neck skin. The changes in skin elasticity may effectively predict neck aging before the onset of most of the neck aging signs.
由于改善颈部皱纹的需求不断增加，颈部皮肤老化受到皮肤科学家和皮肤科医生的特别关注。本研究旨在确定中国女性的颈部老化特征，并研究颈部皮肤的临床变化以及机械、地形和生物物理特性。
共有450名中国女性（年龄范围：16 - 66岁）接受了临床检查，并由同一位皮肤科医生使用标准化照片进行分级。皮肤特性通过非侵入性皮肤测量设备进行评估。
结果表明，不同的颈部老化迹象，包括颈部横纹、颈部松弛、消瘦颈部凹陷、颈阔肌带和颈部纹理，出现在不同年龄段，并且自出现以来均随年龄增长而恶化。在大多数老化迹象出现之前，皮肤弹性就有明显变化，并且与年龄以及这些迹象的严重程度均呈负相关。经表皮水分流失（TEWL）与年龄呈正相关，而皮肤水合作用和pH值与年龄无显著相关性。我们还发现皱纹（SEw）和平均粗糙度（Ra）与年龄显著相关。SEw、光滑度、粗糙度平均深度（Rz）、TEWL和红斑指数与颈部横纹、颈部松弛、消瘦颈部凹陷和颈阔肌带的严重程度显著正相关。
这是第一项强调年龄会导致中国女性颈部皮肤出现多种变化的研究。皮肤弹性的变化可能在大多数颈部老化迹象出现之前有效地预测颈部老化。
