Emerg Infect Dis. 2018 Nov;24(11):2003-2009. doi: 10.3201/eid2411.172033. Epub 2018 Nov 17.
In March 2017, a patient became febrile within 4 days after visiting a rustic conference center in Austin, Texas, USA, where Austin Public Health suspected an outbreak of tickborne relapsing fever a month earlier. Evaluation of a patient blood smear and molecular diagnostic assays identified Borrelia turicatae as the causative agent. We could not gain access to the property to collect ticks. Thus, we focused efforts at a nearby public park, <1 mile from the suspected exposure site. We trapped Ornithodoros turicata ticks from 2 locations in the park, and laboratory evaluation resulted in cultivation of 3 B. turicatae isolates. Multilocus sequencing of 3 chromosomal loci (flaB, rrs, and gyrB) indicated that the isolates were identical to those of B. turicatae 91E135 (a tick isolate) and BTE5EL (a human isolate). We identified the endemicity of O. turicata ticks and likely emergence of B. turicatae in this city.
2017 年 3 月，一名患者在美国德克萨斯州奥斯汀的一个乡村会议中心参观后 4 天内出现发热症状，此前一个月奥斯汀公共卫生部门怀疑该会议中心发生了蜱传回归热疫情。对患者血液涂片和分子诊断检测的评估结果表明，导致该病的病原体为土耳其包柔螺旋体。我们无法进入该场所采集蜱虫。因此，我们将工作重点放在距离疑似暴露地点不到 1 英里的附近一个公共公园。我们从公园的 2 个地点诱捕了土耳其钝眼蜱，并对实验室评估结果进行了培养，共分离出 3 株 B. turicatae 分离株。对 3 个染色体基因座（flaB、rrs 和 gyrB）的多位点测序结果表明，分离株与 B. turicatae 91E135（蜱分离株）和 BTE5EL（人分离株）相同。我们确定了土耳其钝眼蜱的流行地区，以及该城市 B. turicatae 的可能出现。
