Opt Lett. 2018 Sep 1;43(17):4224-4227. doi: 10.1364/OL.43.004224.
Aberration-corrected imaging of human photoreceptor cells, whether hardware or software based, presently requires a complex and expensive setup. Here we use a simple and inexpensive off-axis full-field time-domain optical coherence tomography (OCT) approach to acquire volumetric data of an in vivo human retina. Full volumetric data are recorded in 1.3 s. After computationally correcting for aberrations, single photoreceptor cells were visualized. In addition, the numerical correction of ametropia is demonstrated. Our implementation of full-field optical coherence tomography combines a low technical complexity with the possibility for computational image correction.
目前,基于硬件或软件的人眼感光细胞像差校正成像都需要复杂且昂贵的设备。在此,我们采用一种简单、经济的离轴全场时域光学相干层析成像(OCT)方法获取活体人眼视网膜的容积数据。1.3 秒内可完成全容积数据采集。经像差计算校正后,可显示单个感光细胞。此外,还展示了对屈光不正的数值校正。我们的全场光学相干层析成像技术将低技术复杂性与计算图像校正的可能性相结合。