Suppr超能文献

一例同时诊断为多菌型麻风病患者出现IgA沉积的快速进行性肾小球肾炎所致急性肾衰竭:病例报告

Acute renal failure by rapidly progressive glomerulonephritis with IgA deposition in a patient concomitantly diagnosed with multibacillary Hansen's disease: a case report.

作者信息

Parente Yuri de Deus Mont'alverne, Castro Amanda Lopes de, Araújo Flávio Bezerra de, Teixeira André Costa, Lima Ítalo Criszostomo, Daher Elizabeth De Francesco

机构信息

Hospital Geral Dr. Waldemar Alcântara, Departamento de Clínica Médica, Fortaleza, CE, Brasil.

Hospital Geral Dr. Waldemar Alcântara, Fortaleza, CE, Brasil.

出版信息

J Bras Nefrol. 2019 Jan-Mar;41(1):152-156. doi: 10.1590/2175-8239-jbn-2018-0056. Epub 2018 Aug 23.

Abstract

Rapidly progressive glomerulonephritis (RPGN) is a renal disease with an extensive differential diagnosis. This paper reports the case of a 55-year-old female patient diagnosed with Hansen's disease with acute progressive renal impairment after developing lower limb pyoderma. The association between Hansen's and kidney disease has been well documented, with glomerulonephritis (GN) ranked as the most common form of renal involvement. Post-infectious glomerulonephritis (PIGN) in adults has been associated with a number of pathogens occurring in diverse sites. The patient described in this case report had RPGN and biopsy findings suggestive of PIGN with C3 and IgA detected on immunofluorescence and kidney injury secondary to recent infection by Staphylococcus, a well-documented manifestation of renal impairment in patients with Hansen's disease.

摘要

急进性肾小球肾炎(RPGN)是一种需要进行广泛鉴别诊断的肾脏疾病。本文报告了一例55岁女性患者的病例,该患者在出现下肢脓疱病后被诊断为汉森病并伴有急性进行性肾功能损害。汉森病与肾脏疾病之间的关联已有充分记录,肾小球肾炎(GN)是肾脏受累最常见的形式。成人感染后肾小球肾炎(PIGN)与多种部位出现的多种病原体有关。本病例报告中描述的患者患有RPGN,活检结果提示为PIGN,免疫荧光检测发现C3和IgA,肾脏损伤继发于近期金黄色葡萄球菌感染,这是汉森病患者肾功能损害的一种已充分记录的表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b0/6534021/e0eb71079919/2175-8239-jbn-2018-0056-gf01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验