Department of Microbiology, Global Health, and Medicine, University of Washington, Seattle, WA, USA.
Departments of Laboratory Medicine, Global Health, and Medicine, University of Washington, Seattle, WA, USA.
Bioinformatics. 2019 Mar 15;35(6):1073-1075. doi: 10.1093/bioinformatics/bty712.
We introduce ISDB, a set of software tools for the creation and administration of relational databases of viral integration site (IS) data. Using ISDB, investigators can curate a private database from any heterogeneous set of data sources, including previously-published datasets and internal, work-in-progress data. To make data visible and accessible to collaborators with varying degrees of computational expertise, ISDB automatically generates web sites describing database contents and data exports in several common formats. Compared to a public depository database, the ability to build local, private databases makes ISDB suitable for use in testing hypotheses and developing analyses in the long pre-publication phase of most research.
Installation and usage documentation for ISDB are provided on our website https://mullinslab.microbiol.washington.edu/isdb/. Source code is available under the open source MIT license from https://github.com/MullinsLab/ISDB.
Supplementary data are available at Bioinformatics online.
我们介绍了 ISDB,这是一套用于创建和管理病毒整合位点 (IS) 数据的关系数据库的软件工具。使用 ISDB,研究人员可以从任何异构数据源(包括以前发表的数据集和内部的、正在进行的工作数据)中整理私人数据库。为了使具有不同计算专业知识的合作者能够看到和访问数据,ISDB 会自动生成描述数据库内容和以几种常见格式导出数据的网站。与公共存储库数据库相比,构建本地私人数据库的能力使 ISDB 适合在大多数研究的预发表阶段测试假设和开发分析。
我们的网站 https://mullinslab.microbiol.washington.edu/isdb/ 提供了 ISDB 的安装和使用文档。源代码可在开放源代码 MIT 许可证下从 https://github.com/MullinsLab/ISDB 获得。
补充数据可在 Bioinformatics 在线获得。