Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Surg Obes Relat Dis. 2018 Oct;14(10):1594-1599. doi: 10.1016/j.soard.2018.07.008. Epub 2018 Jul 31.
Pregnancy outcomes after bariatric surgery have been addressed extensively; however, the impact of pregnancy on long-term outcomes after bariatric surgery has only been sparsely studied.
We explored the effects of pregnancy on weight loss outcomes after laparoscopic sleeve gastrectomy (LSG).
University hospital.
A cross-sectional case-control study. Eighty women who became pregnant after LSG were matched by preoperative body mass index, age, and follow-up duration to 80 post-LSG patients who did not conceive after surgery (control group).
The median follow-up duration was 5.2 years for the study group and 5.3 years for the control group (P = .73). For the study group, the median time from surgery to conception was 508 (interquartile range 372-954) days and the median gestational weight gain was 9 (6-12) kg. Comparing the study with the control group, median percentage total weight loss was similar, 31% versus 30% (P = .77); as was percentage excess weight loss (EWL%) 72% versus 71% (P = .77). For the study group, a multivariable analysis showed EWL% at the end of follow-up to be directly correlated with the lowest EWL% achieved before pregnancy (β = .78, P < .0001), and inversely correlated with time lapsed from surgery (β = -.26, P < .0001); yet EWL% was not found to be associated with surgery-to-conception time interval, gestational weight gain, breastfeeding, co-morbidities, smoking, occupational status, physical activity, and dietary habits.
Pregnancy after LSG does not affect long-term weight results. Coupled with the positive reports of improved pregnancy outcomes after bariatric surgery, these data should reassure women who wish to conceive after surgery.
减重手术后的妊娠结局已得到广泛研究；然而，妊娠对减重手术后长期结局的影响仅得到了少量研究。
我们探讨了妊娠对腹腔镜袖状胃切除术（LSG）后减肥效果的影响。
大学医院。
一项回顾性病例对照研究。将 80 名 LSG 后怀孕的女性与 80 名术后未怀孕的 LSG 患者（对照组）进行配对，匹配术前体重指数、年龄和随访时间。
研究组的中位随访时间为 5.2 年，对照组为 5.3 年（P=0.73）。对于研究组，从手术到怀孕的中位时间为 508 天（四分位间距 372-954 天），中位妊娠体重增加为 9 公斤（6-12 公斤）。与对照组相比，研究组的中位总体重减轻百分比相似，为 31%比 30%（P=0.77）；体重减轻百分比（EWL%）也相似，为 72%比 71%（P=0.77）。对于研究组，多变量分析显示，随访结束时的 EWL%与妊娠前最低 EWL%呈直接相关（β=0.78，P<0.0001），与手术至随访时间呈负相关（β=-0.26，P<0.0001）；然而，未发现 EWL%与手术至妊娠时间间隔、妊娠体重增加、母乳喂养、合并症、吸烟、职业状态、体力活动和饮食习惯有关。
LSG 后妊娠不会影响长期减肥效果。结合减重手术后妊娠结局改善的积极报告，这些数据应使希望术后怀孕的女性安心。
