Department of Medicine, MGH Weight Center, Boston, MA, USA.
Division of Pediatric Endocrinology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Expert Rev Endocrinol Metab. 2021 May;16(3):123-134. doi: 10.1080/17446651.2021.1914585. Epub 2021 Apr 21.
: Rates of severe obesity in adolescents have increased at an alarming rate. Unfortunately, there are limited successful treatments for severe obesity in adolescents. Metabolic and bariatric surgery (MBS) is the most effective treatment available for adolescents with Class 2 and above severe obesity and has demonstrated variable degrees of sustained long-term weight loss which leads to resolution of multiple associated conditions and an improved quality of life.: We discuss the current landscape of MBS in adolescents and evidence to support its long-term safety and efficacy. A literature search through PubMed, ResearchGate and HOLLIS Harvard Library Online Catalog was performed from the date of inception until 3/15/2021. A combination of the following keywords was used: Pediatric metabolic/bariatric surgery; long term outcomes of Pediatric metabolic/bariatric surgery, perioperative assessment, pediatric metabolic/bariatric surgery barriers; attitudes toward metabolic/bariatric surgery.: MBS is emerging as a safe and effective treatment strategy for adolescents with severe obesity, with recent studies demonstrating durable and sustainable weight loss. There remains an urgent need for longitudinal studies to assess durability of weight loss. Obesity stigma and bias, limited access to tertiary care centers, and skepticism around the treatment of obesity poses a major challenge.
青少年重度肥胖的发生率呈惊人的速度增长。不幸的是,对于青少年重度肥胖症,目前成功的治疗方法有限。代谢和减重手术(MBS)是目前针对 2 级及以上重度肥胖青少年最有效的治疗方法,已证实能持续长期减轻体重,从而解决多种相关疾病并提高生活质量。我们讨论了青少年 MBS 的现状以及支持其长期安全性和疗效的证据。从成立日期到 2021 年 3 月 15 日,通过 PubMed、ResearchGate 和 HOLLIS 哈佛图书馆在线目录进行了文献检索。使用了以下关键词的组合:儿科代谢/减重手术;儿科代谢/减重手术的长期结果、围手术期评估、儿科代谢/减重手术的障碍;对代谢/减重手术的态度。MBS 作为一种治疗青少年重度肥胖症的安全有效的治疗策略,最近的研究显示了持久和可持续的体重减轻。仍然迫切需要进行纵向研究来评估体重减轻的持久性。肥胖耻辱和偏见、获得三级护理中心的机会有限以及对肥胖治疗的怀疑,这构成了一个主要挑战。
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