Dvorák M
Vet Med (Praha). 1986 Jul;31(7):403-14.
The concentrations of total protein (TP), albumin and globulin in the blood serum were investigated in seven trials with 203 piglets weaned at the age of three to four weeks. The lowest values were recorded in the newborn piglets just before colostrum intake. Two days later the TP level was three times higher and that of globulin almost five times higher. Later the levels began to sink (more intensively in globulin) and the decrease lasted until the end of the second month of age. Albuminaemia increased from birth until the end of study (the beginning of the third month) without any greater influence of colostrum intake and at a rate reduced by weaning. The albumin-globulin quotient, the lowest on the second day of life, increased step by step. The better-growing piglets mostly had higher albuminaemia and their hypoglobulinaemia reached a normal level sooner after weaning as compared with the tail-enders. This suggests that nutrition, body growth and albumin and globulin synthesis are interdependent in piglets. An increase in serum corticosteroids induced by two days of starvation or two administrations of adrenocorticotropic hormone, caused an insignificant increase in the concentration of albumin. Two hours after ACTH administration, the high level of corticosteroids was not observed to be accompanied by a change in serum proteins.
在七项试验中，对203头3至4周龄断奶的仔猪血清中的总蛋白（TP）、白蛋白和球蛋白浓度进行了研究。刚出生的仔猪在摄入初乳前，这些指标值最低。两天后，TP水平升高了两倍，球蛋白水平几乎升高了五倍。随后这些水平开始下降（球蛋白下降更明显），且这种下降一直持续到仔猪2月龄结束。从出生到研究结束（第三个月初），血清白蛋白水平一直在上升，初乳摄入对此没有太大影响，且断奶使其上升速率有所降低。白蛋白与球蛋白的比值在出生第二天最低，之后逐步上升。生长较好的仔猪大多血清白蛋白水平较高，与生长落后的仔猪相比，它们断奶后低球蛋白血症更快恢复到正常水平。这表明仔猪的营养、身体生长以及白蛋白和球蛋白的合成是相互依存的。两天饥饿或两次注射促肾上腺皮质激素所诱导的血清皮质类固醇增加，导致白蛋白浓度出现不显著的升高。注射促肾上腺皮质激素两小时后，未观察到高皮质类固醇水平伴随着血清蛋白的变化。
