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超声引导与单纯临床评估在小儿皮肤和软组织感染管理中的比较。

Comparison of Ultrasound Guidance vs. Clinical Assessment Alone for Management of Pediatric Skin and Soft Tissue Infections.

作者信息

Lam Samuel H F, Sivitz Adam, Alade Kiyetta, Doniger Stephanie J, Tessaro Mark O, Rabiner Joni E, Arroyo Alexander, Castillo Edward M, Thompson Caroline A, Yang Mingan, Mistry Rakesh D

机构信息

Department of Emergency Medicine, University of California at San Diego, San Diego, California.

Department of Emergency Medicine, Newark Beth Israel Medical Center, Newark, New Jersey.

出版信息

J Emerg Med. 2018 Nov;55(5):693-701. doi: 10.1016/j.jemermed.2018.07.010. Epub 2018 Aug 28.

Abstract

BACKGROUND

Point-of-care ultrasound (POCUS) can potentially help distinguish cellulitis from abscess, which can appear very similar on physical examination but necessitate different treatment approaches.

OBJECTIVE

To compare POCUS guidance vs. clinical assessment alone on the management of pediatric skin and soft tissue infections (SSTI) in the emergency department (ED) setting.

METHODS

Children ages 6 months to 18 years presenting to participating EDs with SSTIs ≥ 1 cm were eligible. All treatment decisions, including use of POCUS, were at the discretion of the treating clinicians. Patients were divided into those managed with POCUS guidance (POCUS group) and those managed using clinical assessment alone (non-POCUS group). Primary outcome was clinical treatment failure at 7-10 days (unscheduled ED return visit or admission, procedural intervention, change in antibiotics therapy). Secondary outcomes were ED length of stay, discharge rate, use of alternative imaging, and need for procedural sedation. POCUS utility and impact on management decisions were also assessed by treating clinicians.

RESULTS

In total, 321 subjects (327 lesions) were analyzed, of which 299 (93%) had completed follow-up. There was no significant difference between the POCUS and non-POCUS groups in any of the primary or secondary outcomes. Management plan was changed in the POCUS group in 22.9% of cases (13.8% from medical to surgical, 9.1% from surgical to medical). Clinicians reported increased benefit of POCUS in cases of higher clinical uncertainty.

CONCLUSIONS

Use of POCUS was not associated with decreased ED treatment failure rate or process outcomes in pediatric SSTI patients. However, POCUS changed the management plan in approximately one in four cases.

摘要

背景

床旁超声(POCUS)可能有助于区分蜂窝织炎和脓肿,这两种病症在体格检查中可能非常相似,但需要不同的治疗方法。

目的

比较在急诊科(ED)环境中,POCUS引导与单纯临床评估对小儿皮肤和软组织感染(SSTI)管理的效果。

方法

年龄在6个月至18岁、因SSTI且病变≥1厘米到参与研究的急诊科就诊的儿童符合条件。所有治疗决策,包括POCUS的使用,均由主治临床医生自行决定。患者被分为接受POCUS引导治疗的患者(POCUS组)和仅接受临床评估治疗的患者(非POCUS组)。主要结局是7至10天的临床治疗失败(非计划的急诊复诊或住院、程序性干预、抗生素治疗改变)。次要结局包括急诊留观时间、出院率、替代成像的使用以及程序性镇静的需求。主治临床医生还评估了POCUS的实用性及其对管理决策的影响。

结果

总共分析了321名受试者(327个病灶),其中299名(93%)完成了随访。POCUS组和非POCUS组在任何主要或次要结局方面均无显著差异。POCUS组在22.9%的病例中改变了管理计划(13.8%从内科治疗改为外科治疗,9.1%从外科治疗改为内科治疗)。临床医生报告称,在临床不确定性较高的病例中,POCUS的益处更大。

结论

在小儿SSTI患者中,使用POCUS与降低急诊治疗失败率或改善治疗过程结局无关。然而,POCUS在约四分之一的病例中改变了管理计划。

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