Getabelew Aytenew, Aman Mihret, Fantaye Endashaw, Yeheyis Tomas
Department of Nursing, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia.
Department of Nursing, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.
Int J Pediatr. 2018 Aug 2;2018:7801272. doi: 10.1155/2018/7801272. eCollection 2018.
Neonatal sepsis is an important cause of morbidity and mortality among neonates in developing countries accounting for 30-50% of total deaths each year. Childhood mortality is often used as broad indicator of the social development or a specific indicator of health conditions of a country.
The objective of this study is to assess the prevalence of neonatal sepsis and associated factors among neonates admitted in neonatal intensive care unit at two hospitals in Shashemene town, Ethiopia.
An institution based cross-sectional study with retrospective document review method was conducted in NICUs of two governmental hospitals in Shashemene town. Sample size was calculated by using single population proportion sample formula and the final sample size was 244. The study subject was selected by using systematic random sampling method, and adopted data collection tool was used. Then the collected data was coded and entered in to SPSS for windows version 20.0 for cleaning, editing, and analysis. Binary and multiple logistic regressions have been used to observe the association between independent variables and dependent variable.
The overall prevalence of neonatal sepsis in this study was 77.9%. From this 65% and 35% of neonates developed early onset neonatal sepsis and late onset neonatal sepsis, respectively. This study found out that age of neonates, birth asphyxia, and use of oxygen via mask were significantly associated with neonatal sepsis. The most risk factors of neonatal sepsis were identified as age of neonates, birth asphyxia, and use of oxygen via mask strongly associated with prevalence of NS. Based on this results we recommend the concerned body to focus on the prevention of risk factors rather than treating the disease after it occurs.
新生儿败血症是发展中国家新生儿发病和死亡的重要原因，每年占总死亡人数的30%-50%。儿童死亡率常被用作一个国家社会发展的广泛指标或健康状况的具体指标。
本研究的目的是评估埃塞俄比亚沙舍梅内镇两家医院新生儿重症监护病房收治的新生儿中新生儿败血症的患病率及相关因素。
在沙舍梅内镇两家政府医院的新生儿重症监护病房进行了一项基于机构的横断面研究，并采用回顾性文献复习方法。使用单总体比例抽样公式计算样本量，最终样本量为244。采用系统随机抽样方法选择研究对象，并使用采用的数据收集工具。然后将收集到的数据进行编码，并录入SPSS for windows 20.0版本进行清理、编辑和分析。采用二元和多元逻辑回归分析观察自变量与因变量之间的关联。
本研究中新生儿败血症的总体患病率为77.9%。其中，分别有65%和35%的新生儿发生早发型新生儿败血症和晚发型新生儿败血症。本研究发现，新生儿年龄、出生窒息和面罩吸氧与新生儿败血症显著相关。新生儿败血症的最危险因素被确定为新生儿年龄、出生窒息和面罩吸氧，它们与新生儿败血症的患病率密切相关。基于这些结果，我们建议相关机构关注危险因素的预防，而不是在疾病发生后进行治疗。
