School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, MG, Brazil.
Laboratory of Cardiorespiratory and Metabolic Physiology, Department of Physical Education, Federal University of Uberlandia (UFU), Uberlandia, MG, Brazil.
Exp Gerontol. 2019 Mar;117:31-37. doi: 10.1016/j.exger.2018.08.007. Epub 2018 Sep 1.
The aim of this study was to evaluate the effect of isoflavone supplementation plus combined exercise protocol on phase angle (PhA) values in postmenopausal women.
Thirty postmenopausal women were randomly assigned in a double blind, placebo-controlled clinical trial divided into two groups: 100 mg/day of isoflavone supplementation (n = 16) and 100 mg/day of starch (placebo; n = 14). In addition, both groups performed a combined aerobic and resistance exercise during 10 weeks. Body composition and PhA were evaluated by bioelectrical impedance.
PhA values did not change in the isoflavone group (PRE: 6.7 ± 0.7° to POST: 6.7 ± 0.6°) and in the placebo group (PRE: 7.2 ± 1.0° to POST: 6.8 ± 0.5°); p group = 0.304, p time = 0.227, p group x time interaction = 0.137. Additionally, delta values were not different (0.04 ± 0.5° vs. -0.40 ± 0.99°; p = 0.176) between isoflavone and placebo groups, respectively.
We conclude that isoflavone supplementation plus combined aerobic and resistance exercise did not change PhA in postmenopausal women. The patients were part of ClinicalTrials.gov: NCT03008785.
本研究旨在评估异黄酮补充剂联合综合运动方案对绝经后妇女相位角（PhA）值的影响。
30 名绝经后妇女被随机分为双盲、安慰剂对照临床试验的两组：每天 100mg 异黄酮补充剂（n=16）和每天 100mg 淀粉（安慰剂；n=14）。此外，两组均在 10 周内进行有氧和抗阻运动的综合训练。身体成分和 PhA 通过生物电阻抗进行评估。
异黄酮组的 PhA 值没有变化（PRE：6.7±0.7°至 POST：6.7±0.6°），安慰剂组也没有变化（PRE：7.2±1.0°至 POST：6.8±0.5°）；p 组=0.304，p 时间=0.227，p 组 x 时间交互作用=0.137。此外，异黄酮组和安慰剂组的 delta 值也没有差异（0.04±0.5° vs. -0.40±0.99°；p=0.176）。
我们得出结论，异黄酮补充剂联合综合有氧和抗阻运动不会改变绝经后妇女的 PhA 值。该研究已在 ClinicalTrials.gov 注册：NCT03008785。
