（D-苯丙氨酸-7）促肾上腺皮质激素4-10诱导的过度梳理行为的特征。

Character of (D-Phe-7) ACTH4-10-induced excessive grooming.

作者信息

Isaacson R L, Thomas J

出版信息

Exp Neurol. 1986 Sep;93(3):657-61. doi: 10.1016/0014-4886(86)90186-x.

Abstract

Rats receiving (D-Phe-7) ACTH4-10 exhibited excessive grooming during the first half of the hour-long observation period. This resulted in total grooming scores of about one-half of those produced by the longer ACTH fragments, ACTH1-24 or ACTH1-16 NH2. The excessive grooming induced by (D-Phe-7) ACTH4-10 was due to an enhancement of duration of grooming bouts and not to an increase in the frequency of occurrence. Furthermore, the neuropeptide-induced excessive grooming was eliminated by prior treatment with naloxone.

摘要

接受（D-苯丙氨酸-7）促肾上腺皮质激素4-10的大鼠在长达一小时的观察期的前半段表现出过度梳理行为。这导致总的梳理得分约为较长的促肾上腺皮质激素片段促肾上腺皮质激素1-24或促肾上腺皮质激素1-16 NH2所产生得分的一半。（D-苯丙氨酸-7）促肾上腺皮质激素4-10诱导的过度梳理是由于梳理发作持续时间的延长，而不是发生频率的增加。此外，用纳洛酮预先处理可消除神经肽诱导的过度梳理行为。