International Clinical Research Center, St Anne's University Hospital, 65691 Brno, Czech Republic.
Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.
Nutrients. 2018 Sep 3;10(9):1219. doi: 10.3390/nu10091219.
In the European Union, Czech Republic ranks 3rd and 6th for the incidence of obesity and cardiovascular diseases, respectively. Worldwide, short sleep duration and excessive daytime sleepiness (EDS) characterize obese subjects, which in turn exhibit scarce physical activity and unhealthy diet. We aimed to understand the relationship between irregular sleep patterns, obesity and lifestyle factors, such as diet and physical activity, in a vulnerable Czech population. 1482 members of the Kardiovize cohort, a random sample of the Czech urban population, were included in a cross-sectional study. Exposure variables included self-reported sleep duration and EDS, assessed by the Epworth Sleepiness Scale. Primary outcomes were BMI and waist-to-hip ratio or prevalence of obesity and central obesity. Covariates included physical activity and diet. Associations and interactions between variables were evaluated using logistic regression analyses. After adjustment for covariates, short sleep duration (<7 h) was associated with greater odds of overweight (BMI > 25; OR = 1.42; 95%CI = 1.06⁻1.90; = 0.020) and obesity (BMI > 30; OR = 1.40; 95%CI = 1.02⁻1.94; = 0.047), while EDS was associated with greater odds of central obesity (OR = 1.72; 95%CI = 1.06⁻2.79; = 0.030), independent of diet and physical activity. However, due to the cross-sectional nature of our study, further prospective, large-scale studies are needed to evaluate the etiological link and causality between sleep disturbances and obesity.
在欧盟,捷克共和国的肥胖症和心血管疾病的发病率分别排名第 3 位和第 6 位。在全球范围内,肥胖症患者的睡眠时间短且白天过度嗜睡(EDS),而这些人往往身体活动不足,饮食也不健康。我们旨在了解不规律的睡眠模式、肥胖症与生活方式因素(如饮食和身体活动)之间的关系,这些因素在捷克的弱势群体中较为普遍。在一项横断面研究中,我们纳入了 Kardiovize 队列的 1482 名成员,该队列是捷克城市人群的随机样本。暴露变量包括自我报告的睡眠时间和 EDS,通过 Epworth 嗜睡量表进行评估。主要结局指标是 BMI 和腰臀比或肥胖和中心性肥胖的患病率。协变量包括身体活动和饮食。使用逻辑回归分析评估变量之间的关联和相互作用。在调整协变量后,睡眠时间短(<7 小时)与超重(BMI>25;OR=1.42;95%CI=1.06⁻1.90;=0.020)和肥胖(BMI>30;OR=1.40;95%CI=1.02⁻1.94;=0.047)的几率增加相关,而 EDS 与中心性肥胖的几率增加相关(OR=1.72;95%CI=1.06⁻2.79;=0.030),独立于饮食和身体活动。然而,由于我们的研究是横断面研究,因此需要进一步进行前瞻性、大规模的研究,以评估睡眠障碍与肥胖之间的病因联系和因果关系。