饮食炎症指数与多发性硬化症的临床病程。
Dietary Inflammatory Index and clinical course of multiple sclerosis.
机构信息
Postgraduate Program in Public Health, Ceará State University, Av. Dr. Silas Munguba, 1700-Itaperi, Fortaleza, CE, 60741-000, Brazil.
Group of Research in Nutrition and Chronic Diseases, Ceará State University, Av. Dr. Silas Munguba, 1700-Itaperi, Fortaleza, CE, 60741-000, Brazil.
出版信息
Eur J Clin Nutr. 2019 Jul;73(7):979-988. doi: 10.1038/s41430-018-0294-8. Epub 2018 Sep 3.
OBJECTIVES
This study aims at analyzing the association between the Dietary Inflammatory Index (DII) and the clinical condition of multiple sclerosis (MS) patients.
METHODS
It is a quantitative, cross-sectional analytical study that included 137 MS patients assisted at a reference center for MS treatment in the Brazilian northeast. Data was collated through a structured questionnaire and medical records consultation, also involving demographic, clinical, and nutritional variables. Clinical variables included the MS type, diagnosis and follow-up start dates, investigation of recent urinary tract symptoms, use of immunomodulatory, vitamin D supplementation, number of recent pulse therapies, relapse rate in the last 2 years, muscular strength assessment (MRC), disability degree (EDSS), and a gadolinium-enhanced magnetic resonance imaging (MRI) scan in the central white matter (CWM). The DII was calculated according to the Shivappa et al. methodology.
RESULTS
There was no difference in any of the variables according to the DII (p > 0.05).
CONCLUSIONS
The Dietary Inflammatory Index did not affect the clinical condition of individuals with multiple sclerosis.
目的
本研究旨在分析饮食炎症指数（DII）与多发性硬化症（MS）患者临床状况之间的关联。
方法
这是一项定量、横断面分析研究，纳入了 137 名在巴西东北部多发性硬化症治疗参考中心接受治疗的 MS 患者。通过结构化问卷和病历查阅收集数据，还涉及人口统计学、临床和营养变量。临床变量包括 MS 类型、诊断和随访开始日期、近期尿路症状调查、使用免疫调节剂、维生素 D 补充剂、最近脉冲治疗次数、过去 2 年内的复发率、肌肉力量评估（MRC）、残疾程度（EDSS）以及中央白质的钆增强磁共振成像（MRI）扫描。DII 根据 Shivappa 等人的方法进行计算。
结果
根据 DII，任何变量之间均无差异（p>0.05）。
结论
饮食炎症指数不会影响多发性硬化症患者的临床状况。
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