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少数民族身份和移民身份是一般人群出现精神病症状的风险因素:一项荟萃分析。

Ethnic minority position and migrant status as risk factors for psychotic symptoms in the general population: a meta-analysis.

机构信息

Centre Hospitalier Le Vinatier,Bron,France.

Centre Hospitalier Saint Jean de Dieu,Lyon,France.

出版信息

Psychol Med. 2019 Mar;49(4):545-558. doi: 10.1017/S0033291718002271. Epub 2018 Sep 4.

DOI:10.1017/S0033291718002271
PMID:30178719
Abstract

Psychotic symptoms (PS) are experienced by a substantial proportion of the general population. When not reaching a threshold of clinical relevance, these symptoms are defined as psychotic experiences (PEs) and may exist on a continuum with psychotic disorders. Unfavorable socio-environmental conditions, such as ethnic minority position (EMP) and migrant status (MS), may increase the risk of developing PS and PEs. We conducted an electronic systematic review and a meta-analysis assessing the role of EMP and MS for the development and persistence of PS in the general population. Sub-group analyses were performed investigating the influence of ethnic groups, host countries, age, types of PS, and scales. Twenty-four studies met our inclusion criteria. EMP was a relevant risk factor for reporting PS [odds ratio (OR) 1.44, 95% confidence interval (CI) 1.22-1.70) and PEs (OR 1.36, 95% CI 1.16-1.60). The greatest risk was observed in people from the Maghreb and the Middle East ethnic groups in Europe (OR 3.30, 95% CI 2.09-5.21), in Hispanic in the USA (OR 1.98, 95% CI 1.43-2.73), and in the Black populations (OR 1.85, 95% CI 1.39-2.47). We found a significant association between MS and delusional symptoms (OR 1.47, 95% CI 1.33-1.62). We found no association between EMP and persistence of PEs.EMP was associated with increased risk of reporting PS and PEs, and the risk was higher in ethnic groups facing deprivation and discrimination. We found an association between MS and delusional symptoms. These results raise questions about the precise role of socio-environmental factors along the psychosis continuum.

摘要

大量人群会经历精神病性症状 (PS)。当这些症状未达到临床相关阈值时,被定义为精神病性体验 (PEs),并且可能与精神病性障碍呈连续谱关系。不利的社会环境条件,如少数民族地位 (EMP) 和移民身份 (MS),可能会增加发展 PS 和 PEs 的风险。我们进行了电子系统综述和荟萃分析,评估 EMP 和 MS 对一般人群中 PS 的发展和持续存在的作用。进行了亚组分析,以研究族裔群体、东道国、年龄、PS 类型和量表对其的影响。符合纳入标准的研究有 24 项。EMP 是报告 PS 的一个相关风险因素 [比值比 (OR) 1.44,95%置信区间 (CI) 1.22-1.70] 和 PEs (OR 1.36,95% CI 1.16-1.60)。在来自欧洲马格里布和中东族裔群体的人群中观察到最大的风险 (OR 3.30,95% CI 2.09-5.21)、在美国的西班牙裔人群中 (OR 1.98,95% CI 1.43-2.73) 和黑人人群中 (OR 1.85,95% CI 1.39-2.47)。我们发现 MS 与妄想症状之间存在显著关联 (OR 1.47,95% CI 1.33-1.62)。我们没有发现 EMP 与 PEs 持续存在之间的关联。EMP 与报告 PS 和 PEs 的风险增加相关,而在面临贫困和歧视的族裔群体中风险更高。我们发现 MS 与妄想症状之间存在关联。这些结果引发了关于社会环境因素在精神病连续谱中的确切作用的问题。

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