1Public Health and Environmental Care Unit,Department of Preventive Medicine and Public Health,University of Valencia,Av. Vicente Andrés Estellés s/n,Burjassot 46100,Spain.
3Laboratorio de Salud Pública, Consellería de Sanidad Universal y Salud Pública de la Generalitat Valenciana,Valencia,Spain.
Public Health Nutr. 2018 Nov;21(16):2959-2968. doi: 10.1017/S1368980018002033. Epub 2018 Sep 5.
To assess the daily intake of polychlorinated biphenyls not similar to dioxins (NDL-PCB) derived from fish consumption in Spain and compare it with tolerance limits in order to establish a safe threshold so that the nutritional benefits derived from fish consumption may be optimized.
Analysis of NDL-PCB in fish samples and ecological study of the estimated intake of NDL-PCB from fish consumption in different Spanish population groups.
National representative sample of the Spanish population.
The intake of NDL-PCB was estimated in two different scenarios: upper bound (UB) and lower bound (LB). Estimating intake using the average concentration of NDL-PCB found in the fish samples, the intake for 'other children' is estimated as: 1·80 (UB) and 5·33 (LB) ng/kg per d at the 50th percentile (P50); 7·39 (UB) and 21·94 (LB) ng/kg per d at the 95th percentile (P95) of fish consumption. Estimated NDL-PCB intake shoots up in the toddler group, reaching values of 30·43 (UB) and 90·37 (LB) ng/kg per d at P95. Estimated intake values are lower than those previously estimated in Europe, something expected since in previous studies intake was estimated through total diet. In adults, our estimated values are 1·59 (UB) and 4·72 (LB) ng/kg per d at P50; 4·95 (UB) and 14·72 (LB) ng/kg per d at P95.
NDL-PCB concentration in fish is under the tolerance limits in most samples. However, daily intake in consumers of large quantities of fish should be monitored and special attention should be given to the youngest age groups due to their special vulnerability and higher exposure.
评估西班牙人因食用鱼类而摄入的非二恶英多氯联苯（NDL-PCB）的日摄入量，并与耐受限度进行比较，以确定一个安全阈值，从而优化从鱼类消费中获得的营养益处。
分析鱼类样本中的 NDL-PCB，并对不同西班牙人群组从鱼类消费中摄入 NDL-PCB 的情况进行生态研究。
西班牙人口的全国代表性样本。
在两种不同情况下估计了 NDL-PCB 的摄入量：上限（UB）和下限（LB）。使用鱼类样本中发现的 NDL-PCB 的平均浓度来估计摄入量，对于“其他儿童”，在摄入量处于第 50 个百分位数（P50）时，估计摄入量为：1.80（UB）和 5.33（LB）ng/kg/天；在摄入量处于第 95 个百分位数（P95）时，估计摄入量为 7.39（UB）和 21.94（LB）ng/kg/天。在幼儿组中，NDL-PCB 的估计摄入量猛增，在 P95 时达到 30.43（UB）和 90.37（LB）ng/kg/天。估计的摄入量值低于欧洲此前估计的值，这是意料之中的，因为在之前的研究中，摄入量是通过总膳食来估计的。在成年人中，我们估计的摄入量在 P50 时为 1.59（UB）和 4.72（LB）ng/kg/天；在 P95 时为 4.95（UB）和 14.72（LB）ng/kg/天。
大多数样本中鱼类中的 NDL-PCB 浓度低于耐受限度。然而，应监测大量食用鱼类的消费者的日摄入量，并特别关注年龄最小的群体，因为他们特别脆弱，暴露风险更高。
