高危母亲未满足的需求降低了艾滋病毒感染婴儿抗逆转录病毒治疗的成功率。
Unmet needs of high-risk mothers reduce success of antiretroviral treatment in HIV-infected infants.
作者信息
Mvo Z, Ntlantsana V, Bengu N, Millar J, Roider J, Bhoola R, Krishna M, Graza Y, Van Lobenstein J, Kapongo C, Kogielambal C, Sprenger K, Archary M, Ndung'u T, Goulder P
机构信息
Umkhuseli Innovation and Research Management, Pietermaritzburg, South Africa.
出版信息
S Afr Med J. 2018 Jul 25;108(8):609-610. doi: 10.7196/SAMJ.2018.v108i8.13376.
In the era of effective prevention of mother-to-child transmission of HIV, the same psychosocioeconomic factors that predispose to mother-to-child transmission also substantially increase the likelihood of antiretroviral therapy failure in infected infants. For HIV-infected infants to benefit from early infant diagnosis and treatment initiation, into which much funding and effort is now invested, it is vital that these unmet needs of high-risk mothers are urgently attended to. From an ongoing study of early infant diagnosis and treatment following in utero transmission in KwaZulu-Natal, South Africa, we describe four cases to highlight these challenges facing transmitting mothers that contribute to treatment failure in their infants.
在有效预防母婴传播艾滋病毒的时代，那些易导致母婴传播的相同社会经济因素，也会大幅增加受感染婴儿抗逆转录病毒治疗失败的可能性。为了让感染艾滋病毒的婴儿从早期婴儿诊断和治疗启动中受益（目前已在这方面投入了大量资金和精力），迫切关注高危母亲这些未得到满足的需求至关重要。通过对南非夸祖鲁 - 纳塔尔省子宫内传播后早期婴儿诊断和治疗的一项正在进行的研究，我们描述了四个案例，以突出母婴传播母亲所面临的这些挑战，这些挑战导致了她们婴儿的治疗失败。
Zotero 插件