Clinic for Spinal Cord Injuries, Rigshospitalet, , 3100 Hornbaek, Denmark.
J Rehabil Med. 2018 Sep 28;50(9):806-813. doi: 10.2340/16501977-2372.
To explore changes in pain, spasticity, range of motion, activities of daily living, bowel and lower urinary tract function and quality of life of individuals with spinal cord injury following robotic exoskeleton gait training.
Prospective, observational, open-label multicentre study.
Three training sessions per week for 8 weeks using an Ekso™ GT robotic exoskeleton (EKSO Bionics). Included were individuals with recent (<1 year) or chronic (>1 year) injury, paraplegia and tetraplegia, complete and incomplete injury, men and women.
Fifty-two participants completed the training protocol. Pain was reported by 52% of participants during the week prior to training and 17% during training, but no change occurred longitudinally. Spasticity decreased after a training session compared with before the training session (p <0.001), but not longitudinally. Chronically injured participants increased Spinal Cord Independence Measure (SCIM III) from 73 to 74 (p = 0.008) and improved life satisfaction (p = 0.036) over 8 weeks of training. Recently injured participants increased SCIM III from 62 to 70 (p < 0.001), but no significant change occurred in life satisfaction. Range of motion, bowel and lower urinary function did not change over time.
Training seemed not to provoke new pain. Spasticity decreased after a single training session. SCIM III and quality of life increased longitudinally for subsets of participants.
探索脊髓损伤患者接受机器人外骨骼步态训练后疼痛、痉挛、活动范围、日常生活活动、肠和下尿路功能以及生活质量的变化。
前瞻性、观察性、开放性多中心研究。
每周使用 Ekso™ GT 机器人外骨骼（EKSO Bionics）进行 3 次训练，共 8 周。参与者包括近期（<1 年）或慢性（>1 年）损伤、截瘫和四肢瘫、完全和不完全损伤、男性和女性。
52 名参与者完成了训练方案。52%的参与者在训练前一周报告有疼痛，而 17%的参与者在训练期间报告有疼痛，但疼痛无纵向变化。痉挛在训练后单次治疗后较治疗前减少（p<0.001），但无纵向变化。慢性损伤参与者的脊髓独立性评分（SCIM III）从 73 增加到 74（p=0.008），生活满意度（p=0.036）在 8 周的训练中有所提高。近期损伤的参与者的 SCIM III 从 62 增加到 70（p<0.001），但生活满意度无显著变化。活动范围、肠和下尿路功能没有随时间变化。
训练似乎不会引起新的疼痛。单次训练后痉挛减少。SCIM III 和生活质量在部分参与者中随时间纵向增加。
