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一例不寻常的Descemet膜内皮角膜移植术植片坠入玻璃体及其成功取出与存活的病例

An Unusual Case of DMEK Graft Loss into the Vitreous and Its Successful Retrieval and Survival.

作者信息

Helaiwa Khaled, Januschowski Kai, Boden Karl T, Rickmann Annekatrin

机构信息

Knappschaft Eye Clinic Sulzbach, Knappschaft Hospital Saar, Sulzbach/Saar, Germany.

Centre for Ophthalmology, Eberhard-Karls-University Tübingen, Tübingen, Germany.

出版信息

Case Rep Ophthalmol. 2018 Aug 22;9(2):381-387. doi: 10.1159/000492173. eCollection 2018 May-Aug.

DOI:10.1159/000492173
PMID:30186148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6120406/
Abstract

PURPOSE

The aim of this article is to report an unusual case of postoperative graft loss into the vitreous cavity after Descemet membrane endothelial keratoplasty (DMEK) in a patient with an unstable iris-lens diaphragm (scleral-fixated intraocular lens [sf-IOL]) and its successful retrieval with a favourable outcome.

METHODS

This is a retrospective case report.

RESULTS

DMEK procedure was performed in a vitrectomized eye of an 80-year-old woman with pre-existing sf-IOL due to pseudophakic bullous keratopathy. In the setting of an inadvertently created oversized Ando iridectomy and unstable iris-lens diaphragm due to sf-IOL, repeated loss of an anterior chamber gas tamponade occurred. At the 3rd postoperative day, the patient noticed a change in visual perception, and we could detect a loss of the graft into the vitreous via B-scan ultrasound. A 23-G vitrectomy was performed promptly to recover the graft using a bimanual hand-over-hand technique. Six months after DMEK, the patient had a clear cornea without dehiscences with a central corneal thickness of 533 µm and endothelial cell count of 1,219 cells/mm.

CONCLUSIONS

This case demonstrates the possibility of graft recovery from the vitreous after DMEK and subsequent corneal clearing despite unstable iris-lens diaphragm and vitrectomized eye.

摘要

目的

本文旨在报告一例不寻常的病例,该病例为一名虹膜 - 晶状体隔膜不稳定(巩膜固定人工晶状体[sf - IOL])的患者在进行Descemet膜内皮角膜移植术(DMEK)后移植物掉入玻璃体腔,以及成功取出移植物并获得良好预后的情况。

方法

这是一篇回顾性病例报告。

结果

一名80岁女性因人工晶状体性大泡性角膜病变,在已行玻璃体切除术且植入sf - IOL的眼中进行了DMEK手术。由于无意中形成的过大的安藤虹膜切除术以及sf - IOL导致的虹膜 - 晶状体隔膜不稳定,前房气体填塞反复丢失。术后第3天,患者注意到视觉感知发生变化,通过B超超声我们检测到移植物掉入玻璃体。立即进行了23G玻璃体切除术,采用双手交替技术取出移植物。DMEK术后6个月,患者角膜清晰,无裂开,中央角膜厚度为533 µm,内皮细胞计数为1219个细胞/mm²。

结论

该病例表明,尽管存在虹膜 - 晶状体隔膜不稳定和玻璃体切除的眼睛,但DMEK术后仍有可能从玻璃体中恢复移植物并随后使角膜变清。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/3734c969b139/cop-0009-0381-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/7ff867a8e33e/cop-0009-0381-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/6a37087314a8/cop-0009-0381-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/64dd43226a2a/cop-0009-0381-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/3734c969b139/cop-0009-0381-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/7ff867a8e33e/cop-0009-0381-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/6a37087314a8/cop-0009-0381-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/64dd43226a2a/cop-0009-0381-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d00/6120406/3734c969b139/cop-0009-0381-g04.jpg

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Curr Eye Res. 2018 Jan;43(1):12-17. doi: 10.1080/02713683.2017.1368086. Epub 2017 Sep 22.
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Eventual Endothelial Failure After Initial Corneal Clearing After a Detached Endothelial Graft in Fuchs Dystrophy.富克斯角膜内皮营养不良患者行角膜内皮移植片脱离后初始角膜清亮后的最终内皮功能衰竭
Cornea. 2017 Feb;36(2):241-243. doi: 10.1097/ICO.0000000000001081.
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Treatment of Fuchs Endothelial Dystrophy by Descemet Stripping Without Endothelial Keratoplasty.
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Cornea. 2016 Oct;35(10):1267-73. doi: 10.1097/ICO.0000000000000915.
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Novel liquid bubble dissection technique for DMEK lenticule preparation.用于DMEK晶状体准备的新型液体气泡切割技术。
Graefes Arch Clin Exp Ophthalmol. 2016 Sep;254(9):1819-23. doi: 10.1007/s00417-016-3377-z. Epub 2016 May 21.
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